ImmunoCult™-XF T细胞扩增培养基产品图

ImmunoCult™-XF T细胞扩增培养基

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  • 询价
  • STEMCELL Technologies已认证
  • 10981
  • 2026年09月07日
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料

    产品概要

    ImmunoCult™-XF T Cell Expansion Medium is a serum-free and xeno-free medium optimized for the in vitro culture and expansion of human T cells isolated from peripheral blood. Recombinant cytokines, required for the optimal growth and expansion of T cells, have not been added to ImmunoCult™-XF T Cell Expansion Medium. This allows users the flexibility to prepare medium that meets their requirements.

    This product is designed for cell therapy research applications following the recommendations of USP<1043> on Ancillary Materials, and we can currently work with you to qualify this reagent under an approved investigational new drug (IND) or clinical trial application (CTA).

    This product aims to be developed as a cGMP-grade reagent for cellular therapy research. Learn more at www.stemcell.com/t-cell-therapy.

    Advantages:
    • No need to supplement the medium with serum
    • Supports robust T cell expansion with high viability after 10 - 12 days of culture
    • Expanded T cells are able to produce cytokines including IFN-gamma and IL-4 upon restimulation
    • Use with ImmunoCult™ Human T Cell Activators (Catalog #10970 and 10971) for bead-free activation of T cells

    Cell Type:
    T细胞; CD4+T细胞; CD8+T细胞

    Species:
    人

    Formulation:
    无血清; 无异种成分

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    图标文献和实验
    该产品被引用文献
    [1]Dual tumour-myeloid targeting of glioblastoma with GPNMB CAR-T cells
    PMID:42386964Nature2026-08
    [2]Astragaloside IV represses the immune evasion and acidic microenvironment of oral squamous cell carcinoma.
    PMID:41735828Cell Mol Biol Lett2026-02-24
    [3]A combinatorial CAAR-T cell strategy to eliminate factor VIII inhibitors in preclinical models of hemophilia A.
    PMID:41797925iScience2026-02-18
    [4]Endothelium-Treg Communication Through Extracellular Vesicle Transfer Exacerbates Acute Respiratory Distress Syndrome.
    PMID:41656950J Extracell Vesicles2026-02
    [5]BCL-2 Inhibitor Regulates Number, Function, and Antitumor Immunity of T Cells by Influencing Glycolysis in AML.
    PMID:40771037Cancer Sci2025-10
    [6]Exosomes containing long non-coding RNA AGAP2-AS1 promote the differentiation of CD4+ T cells through the miR-424-5p/SGK1 axis in psoriasis.
    PMID:40520230Front Genet2025-05-30
    [7]Ribonuclease 1 Induces T-Cell Dysfunction and Impairs CD8+ T-Cell Cytotoxicity to Benefit Tumor Growth through Hijacking STAT1.
    PMID:39932384Adv Sci (Weinh)2025-04
    [8]Altered Atlas of Exercise-Responsive MicroRNAs Revealing miR-29a-3p Attacks Armored and Cold Tumors and Boosts Anti-B7-H3 Therapy.
    PMID:39845707Research (Wash D C)2025-01-22
    [9]IL-17A promotes tumorigenesis and upregulates PD-L1 expression in non-small cell lung cancer.
    PMID:37978543J Transl Med2023-11-17
    [10]Inhibition of DCLK1 with DCLK1-IN-1 Suppresses Renal Cell Carcinoma Invasion and Stemness and Promotes Cytotoxic T-Cell-Mediated Anti-Tumor Immunity.
    PMID:34830884Cancers (Basel)2021-11-16
    相关实验
    • Science | 破除抑制性肿瘤微环境,改良 CAR-T 可靶向实体瘤

      ,T 细胞的功能、生存和增殖受到细胞因子信号的强烈影响。共同 γ 链(γc)细胞因子家族的成员,包括 IL-2,4,7,9,15,21,在促进 T 细胞生长、肿瘤杀伤以及驱动长效记忆反应等方面发挥着关键作用。 探索正确的细胞因子组合 IL-2 作为最常用且能够快速诱导 T 细胞扩增的白介素,在 CAR-T, TIL ,CIK 等淋巴细胞相关疗法中有着广泛的应用,对于 NK 细胞同样具有诱导活化扩增的能力。在最初一批 CAR-T 的上市产品中,IL-2 在生产流程中扮演着不可或缺的角色

    • 间充质干细胞及其培养基

      的主要特点: 1、适用于骨髓/脐带/脂肪来源的MSC 2、在更短的培养时间内细胞扩增更多 3、细胞倍增速度更快 4、作简便,基础培养补充剂一次性混合后,即可实现培养 5、更低的接种密度,4000个细胞/cm2 6、在细胞传代的整个过程中,都可持免疫表型、多能性及对T细胞的抑制能 7、无血清、无动物源性,成分已知 优点: 1、精确

    • 用 CD3/CD28 做好 T 细胞激活与扩增

      。细胞数量、培养基体积、多聚体用量配比参考以下表格:   培养板 96 孔板 48 孔板 24 孔板 T 细胞数量 5-8×10^4 2-5×10^4 0.5-1×10^6 培养基体积(ml) 0.1-0.2 0.5-1 1-2 CD3/CD28 Streptamer premix(μl) 3 15 30   3. 培养过程中,每天观察

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