PneumaCult™-Ex Plus Medium is a defined, serum- and BPE-free cell culture medium that supports more expansion of primary human airway epithelial cells at each passage, compared to other commercially available expansion media. This medium also supports at least two additional passages of cell expansion with better differentiation potential, defined as the ability to form a pseudostratified mucociliary epithelium at the air-liquid interface (ALI) using PneumaCult™-ALI Medium (Catalog #05001) or a cuboidal epithelium using PneumaCult™-ALI-S Medium (Catalog #05050).
PneumaCult™-Ex Plus and either PneumaCult™-ALI or PneumaCult™-ALI-S constitute a fully integrated BPE-free culture system for in vitro human airway modeling. This robust and defined system is a valuable tool for basic respiratory research, toxicity studies, and drug development.
Advantages: • A defined, serum- and BPE-free cell culture medium that delivers consistent performance • PneumaCult™-Ex Plus Medium supports more cell expansion at each passage compared to other commercially available expansion media • When used together with PneumaCult™-ALI Medium or PneumaCult™-ALI-S Medium, PneumaCult™-Ex Plus Medium supports better ALI differentiation potential even after extended passaging compared to other commercially available expansion media