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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
在-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Mouse IL6 / Interleukin-6 Protein
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
20 µg/100 µg/1 mg
| 规格: | 20 µg | 产品价格: | ¥1580.0 |
|---|---|---|---|
| 规格: | 100 µg | 产品价格: | ¥3980.0 |
| 规格: | 1 mg | 产品价格: | ¥25880.0 |
蛋白名称:IL-6蛋白, IL-6 protein
蛋白构建:A DNA sequence encoding the mouse IL6 (P08505) (Phe25-Thr211) was expressed and purified.
表达宿主:E. coli
蛋白纯度:> 95 % as determined by SDS-PAGE
蛋白活性:Measured in a cell proliferation assay using T1165 mouse plasmacytoma cells. The ED50 for this effect is typically 0.4-2 ng/ml.
蛋白内毒素:Please contact us for more information.
预测N端:Met
蛋白分子量:The recombinant mouse IL6 consists of 188 amino acids and predicts a molecular mass of 21.9 KDa. It migrates as an approximately 22 KDa band in SDS-PAGE under reducing conditions.
蛋白NP号:P08505
蛋白氨基酸序列:Phe25-Thr211
蛋白标签:Native
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验2, Wang Y, et al. Notch signalling regulates steroidogenesis in mouse ovarian granulosa cells.Reproduction, fertility, and development, PubMed ID: 30827331
3, Wang ZY, et al. Axl deficiency promotes the neuroinvasion of Japanese encephalitis virus by enhancing IL-1α production from pyroptotic macrophages.Journal of virology, PubMed ID: 32611752
4, Katashima CK, et al. Evidence for a neuromuscular circuit involving hypothalamic interleukin-6 in the control of skeletal muscle metabolism.Science advances, PubMed ID: 35905178
5, Wang D, et al. IL-1β Is an Androgen-Responsive Target in Macrophages for Immunotherapy of Prostate Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany), PubMed ID: 37092583
6, Xie H, et al. VISTA Deficiency Exacerbates the Development of Pulmonary Fibrosis by Promoting Th17 Differentiation.Journal of inflammation research, PubMed ID: 38911987
Typical modification sites: RGG box or RXR sequence motifs R-arginine, G-glycine, X-any aminoacid. Enzymes catalysing protein arginine methylation: PRMT1 from rat and the human homologue HRMT1L2, human PRMT2 (HRMT1L1), rat and human PRMT
Strategies to Optimize Protein Expression in E. coli
Peng, L., Xu, Z.N., Fang, X.M., Wang, F., Yang, S., and Cen, P.L. 2004. Preferential codons enhancing the expression level of human beta‐defensin‐2 in recombinant Escherichia coli. Protein Pept. Lett. 11:339
Hydrophobicity Profiles for Protein Sequence Analysis
. Biol. 97:237‐256. Finzel, B.C., Clancy, L.L., Holland, D.R., Muchmore, S.W., Watenpaugh, K.D., and Einspahr, H.M. 1989. Crystal structure of recombinant human interleukin‐1β
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