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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Human FCGRT & B2M Heterodimer Protein (His Tag)
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
1.00 mg/10.00 µg/20.00 µg/50.00 µg/100.00 µg
| 规格: | 1.00 mg | 产品价格: | ¥27600.0 |
|---|---|---|---|
| 规格: | 10.00 µg | 产品价格: | ¥2050.0 |
| 规格: | 20.00 µg | 产品价格: | ¥3220.0 |
| 规格: | 50.00 µg | 产品价格: | ¥5170.0 |
| 规格: | 100.00 µg | 产品价格: | ¥4730.0 |
重组人 FCGRT & B2M 异源二聚体 蛋白 (His标签)(产品说明)
蛋白名称:Human FCGRT & B2M Heterodimer Protein (His Tag)
蛋白构建:A DNA sequence encoding the extracellular domain (Met1-Ser297) of human FCGRT (P55899-1) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the human B2M (P61770-1) (Met1-Met119) constructed the plasmid 2. The two plasmids were co-expressed and the FCGRT / B2M heterodimer was purified.
表达宿主:HEK293 Cells
蛋白纯度:> 95 % as determined by SDS-PAGE
蛋白活性:1. Measured by its ability to bind human IgG1 (Cat: 10702-HNAC) in a functional ELISA. 2. Labeled biotin to FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag) by a certain molar ratio; Using the Octet RED System, the affinity constant (Kd) of FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag) bound to Conbercept was 0.1 μM.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Ala 24 & Ile 21
蛋白分子量:The recombinant heterodimer of human FCGRT/B2M comprises 384 (285+99) amino acids and has a calculated molecular mass of 43.5 (31.8+11.7) kDa. The apparent molecular mass of human FCGRT/B2M heterodimer is approximately 35 & 12 kDa respectively in SDS-PAGE under reducing conditions.
蛋白NP号:P55899-1 & P61770-1
蛋白氨基酸序列:Met1-Ser297 & Met1-Met119
蛋白标签:C-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称:Human FCGRT & B2M Heterodimer Protein (His Tag)
蛋白构建:A DNA sequence encoding the extracellular domain (Met1-Ser297) of human FCGRT (P55899-1) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the human B2M (P61770-1) (Met1-Met119) constructed the plasmid 2. The two plasmids were co-expressed and the FCGRT / B2M heterodimer was purified.
表达宿主:HEK293 Cells
蛋白纯度:> 95 % as determined by SDS-PAGE
蛋白活性:1. Measured by its ability to bind human IgG1 (Cat: 10702-HNAC) in a functional ELISA. 2. Labeled biotin to FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag) by a certain molar ratio; Using the Octet RED System, the affinity constant (Kd) of FCGRT & B2M Heterodimer Protein, Human, Recombinant (His Tag) bound to Conbercept was 0.1 μM.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Ala 24 & Ile 21
蛋白分子量:The recombinant heterodimer of human FCGRT/B2M comprises 384 (285+99) amino acids and has a calculated molecular mass of 43.5 (31.8+11.7) kDa. The apparent molecular mass of human FCGRT/B2M heterodimer is approximately 35 & 12 kDa respectively in SDS-PAGE under reducing conditions.
蛋白NP号:P55899-1 & P61770-1
蛋白氨基酸序列:Met1-Ser297 & Met1-Met119
蛋白标签:C-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验该产品被引用文献
1, Latvala S, et al. Distribution of FcRn Across Species and Tissues.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, PubMed ID: 28402755
2, Goulet DR, et al. Towards a combinatorial approach for the prediction of immunoglobulin G half-life and clearance.Drug metabolism and disposition: the biological fate of chemicals, PubMed ID: 30232177
3, Wada R, et al. Influence of N-glycosylation on effector functions and thermal stability of glycoengineered IgG1 monoclonal antibody with homogeneous glycoforms.mAbs, PubMed ID: 30466347
4, Noy-Porat T, et al. Fc-Independent Protection from SARS-CoV-2 Infection by Recombinant Human Monoclonal Antibodies.Antibodies (Basel, Switzerland), PubMed ID: 34842604
5, Zhou F, et al. A Novel Dual-Fc Bispecific Antibody with Enhanced Fc Effector Function.Biochemistry, PubMed ID: 38426700
2, Goulet DR, et al. Towards a combinatorial approach for the prediction of immunoglobulin G half-life and clearance.Drug metabolism and disposition: the biological fate of chemicals, PubMed ID: 30232177
3, Wada R, et al. Influence of N-glycosylation on effector functions and thermal stability of glycoengineered IgG1 monoclonal antibody with homogeneous glycoforms.mAbs, PubMed ID: 30466347
4, Noy-Porat T, et al. Fc-Independent Protection from SARS-CoV-2 Infection by Recombinant Human Monoclonal Antibodies.Antibodies (Basel, Switzerland), PubMed ID: 34842604
5, Zhou F, et al. A Novel Dual-Fc Bispecific Antibody with Enhanced Fc Effector Function.Biochemistry, PubMed ID: 38426700
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FCGRT & B2M Heterodimer重组蛋白|Recombinant Human FCGRT & B2M Heterodimer Protein (His Tag)
¥2050 - 27600








