- ￥1960 - 12740
- Sino Biological
- 北京
- 10201-H02H
- 2025年08月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human HER3 / ErbB3 Protein (ECD, Fc Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/50.00 µg/100.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥12740.0 |
|---|---|---|---|
| 规格： | 50.00 µg | 产品价格： | ￥2310.0 |
| 规格： | 100.00 µg | 产品价格： | ￥1960.0 |
蛋白名称：Human HER3 / ErbB3 Protein (ECD, Fc Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Thr 643) of human ErbB3 (NP_001973.2) precursor was expressed with the C-terminal fused Fc region of human IgG1.
表达宿主：HEK293 Cells
蛋白纯度：> 90 % as determined by SDS-PAGE
蛋白活性：Immobilized HER3/ERBB3 Protein, Human, Recombinant (ECD, hFc Tag)(Cat:10201-H02H) at 2 μg/mL (100 μL/well) can bind NRG1 Beta 1 Protein, Human, Recombinant,Biotinylated(EGF Domain, Avi&Fc Tag)(Cat:11609-H01H-B), the EC50 is 220-1200 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Ser 20
蛋白分子量：The mature recombinant human ErbB3/Fc chimera is a disulfide-linked homodimeric protein after the removal of signal peptide. The monomer consists of 862 amino acids and has a calculated molecular mass of 95.4 kDa. As a result of glycosylation, the recombinant monomer migrates as an approximately 130-140 kDa protein in SDS-PAGE under reducing conditions.
蛋白NP号：NP_001973.2
蛋白氨基酸序列：Met1-Thr643
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验2, Zong HF, et al. A novel bispecific antibody drug conjugate targeting HER2 and HER3 with potent therapeutic efficacy against breast cancer.Acta pharmacologica Sinica, PubMed ID: 38605180
Protein Microarrays for Identification of Novel Extracellular Protein‐Protein Interactions
microbead complexes. (A ) Schematic model of a protein A‐microbead complex with extracellular domain (ECD)‐Fc fusion protein. Protein A is shown attached to the microbead and binding the Fc (blue) domain of the captured bait protein. (B ) Schematic model
Capture and Qualitative Analysis of the Activated Fc Receptor Complex from Live Cells
the isolation of activated Fc receptor complexes from RAW 264.7 macrophages using live?cell affinity receptor chromatography (LARC). The Fc receptor complex is activated and captured by IgG?coated microbeads on the surface of live macrophages. After the cells
Chromatin Interaction Analysis Using Paired‐End Tag Sequencing
Analysis using Paired?End Tag sequencing (ChIA?PET) is a technique developed for large?scale, de novo analysis of higher?order chromatin structures. Cells are treated with formaldehyde to cross?link chromatin interactions, DNA segments bound by protein
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