- ￥1960 - 12740
- Sino Biological
- 北京
- 10201-H02H
- 2025年08月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human HER3 / ErbB3 Protein (ECD, Fc Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/50.00 µg/100.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥12740.0 |
|---|---|---|---|
| 规格： | 50.00 µg | 产品价格： | ￥2310.0 |
| 规格： | 100.00 µg | 产品价格： | ￥1960.0 |
重组人 HER3 / ErbB3 蛋白 (ECD, Fc标签)（产品说明）
蛋白名称：Human HER3 / ErbB3 Protein (ECD, Fc Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Thr 643) of human ErbB3 (NP_001973.2) precursor was expressed with the C-terminal fused Fc region of human IgG1.
表达宿主：HEK293 Cells
蛋白纯度：> 90 % as determined by SDS-PAGE
蛋白活性：Immobilized HER3/ERBB3 Protein, Human, Recombinant (ECD, hFc Tag)(Cat:10201-H02H) at 2 μg/mL (100 μL/well) can bind NRG1 Beta 1 Protein, Human, Recombinant,Biotinylated(EGF Domain, Avi&Fc Tag)(Cat:11609-H01H-B), the EC50 is 220-1200 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Ser 20
蛋白分子量：The mature recombinant human ErbB3/Fc chimera is a disulfide-linked homodimeric protein after the removal of signal peptide. The monomer consists of 862 amino acids and has a calculated molecular mass of 95.4 kDa. As a result of glycosylation, the recombinant monomer migrates as an approximately 130-140 kDa protein in SDS-PAGE under reducing conditions.
蛋白NP号：NP_001973.2
蛋白氨基酸序列：Met1-Thr643
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称：Human HER3 / ErbB3 Protein (ECD, Fc Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Thr 643) of human ErbB3 (NP_001973.2) precursor was expressed with the C-terminal fused Fc region of human IgG1.
表达宿主：HEK293 Cells
蛋白纯度：> 90 % as determined by SDS-PAGE
蛋白活性：Immobilized HER3/ERBB3 Protein, Human, Recombinant (ECD, hFc Tag)(Cat:10201-H02H) at 2 μg/mL (100 μL/well) can bind NRG1 Beta 1 Protein, Human, Recombinant,Biotinylated(EGF Domain, Avi&Fc Tag)(Cat:11609-H01H-B), the EC50 is 220-1200 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Ser 20
蛋白分子量：The mature recombinant human ErbB3/Fc chimera is a disulfide-linked homodimeric protein after the removal of signal peptide. The monomer consists of 862 amino acids and has a calculated molecular mass of 95.4 kDa. As a result of glycosylation, the recombinant monomer migrates as an approximately 130-140 kDa protein in SDS-PAGE under reducing conditions.
蛋白NP号：NP_001973.2
蛋白氨基酸序列：Met1-Thr643
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验该产品被引用文献
1, Ding X, et al. A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity.EBioMedicine, PubMed ID: 32950002
2, Zong HF, et al. A novel bispecific antibody drug conjugate targeting HER2 and HER3 with potent therapeutic efficacy against breast cancer.Acta pharmacologica Sinica, PubMed ID: 38605180
2, Zong HF, et al. A novel bispecific antibody drug conjugate targeting HER2 and HER3 with potent therapeutic efficacy against breast cancer.Acta pharmacologica Sinica, PubMed ID: 38605180
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HER3/ERBB3重组蛋白|Recombinant Human HER3 / ErbB3 Protein (ECD, Fc Tag)
￥1960 - 12740
