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R-Spondin 1/RSPO1重组蛋白|Recombinant Human R-Spondin 1 / RSPO1 Protein

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  • ¥580 - 25880
  • Sino Biological已认证
  • 北京
  • 11083-HNAS
  • 2025年08月12日
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 保存条件

      -20℃ to -80℃

    • 保质期

      12个月

    • 英文名

      Recombinant Human R-Spondin 1 / RSPO1 Protein

    • 库存

      99

    • 供应商

      北京义翘神州科技股份有限公司

    • 规格

      1.00 mg/5.00 µg/20.00 µg/100.00 µg/500.00 µg

    规格:1.00 mg产品价格:¥25880.0
    规格:5.00 µg产品价格:¥580.0
    规格:20.00 µg产品价格:¥1780.0
    规格:100.00 µg产品价格:¥4980.0
    规格:500.00 µg产品价格:¥14480.0

    重组人 R-Spondin 1 / RSPO1 蛋白(产品说明)
    蛋白名称:Human R-Spondin 1 / RSPO1 Protein
    蛋白构建:A DNA sequence encoding the human RSPO1 (NP_001033722.1) (Met1-Ala263) was expressed and purified.
    表达宿主:CHO Stable Cells
    蛋白纯度:≥ 95 % as determined by SDS-PAGE. ≥95% as determined by SEC-HPLC
    蛋白活性:Measured by its ability to induce activation of ßcatenin response in a Topflash Luciferase assay using HEK293T human embryonic kidney cells. The ED50 for this effect is typically 10-80 ng/mL in the presence of 5 ng/mL recombinant mouse Wnt3a.
    蛋白内毒素:< 10 EU per mg protein.
    预测N端:Ser 21
    蛋白分子量:The recombinant human RSPO1 consists of 243 amino acids and has a predicted molecular mass of 26.8 kDa. As a result of glycosylation, the apparent molecular mass of it is approximately 40 and 31 kDa in SDS-PAGE under reducing conditions.
    蛋白NP号:NP_001033722.1
    蛋白氨基酸序列:Met 1-Ala 263
    蛋白标签:Native
    蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

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    图标文献和实验
    该产品被引用文献

    1, Guo Q, et al. Inhibition of SIRT1 promotes taste bud stem cell survival and mitigates radiation-induced oral mucositis in mice.American journal of translational research, PubMed ID: 31497199
    2, Yao Y, et al. Patient-Derived Organoids Predict Chemoradiation Responses of Locally Advanced Rectal Cancer.Cell stem cell, PubMed ID: 31761724
    3, Li Y, et al. Bach2 Deficiency Promotes Intestinal Epithelial Regeneration by Accelerating DNA Repair in Intestinal Stem Cells.Stem cell reports, PubMed ID: 33382975
    4, Hao M, et al. Patient-Derived Organoid Model in the Prediction of Chemotherapeutic Drug Response in Colorectal Cancer.ACS biomaterials science & engineering, PubMed ID: 35696669
    5, Feng J, et al. Feedback activation of EGFR/wild-type RAS signaling axis limits KRASG12D inhibitor efficacy in KRASG12D-mutated colorectal cancer.Oncogene, PubMed ID: 37020035
    6, Rao X, et al. Unveiling Epigenetic Vulnerabilities in Triple-Negative Breast Cancer through 3D Organoid Drug Screening.Pharmaceuticals (Basel, Switzerland), PubMed ID: 38399440

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    文献支持
    R-Spondin 1/RSPO1重组蛋白|Recombinant Human R-Spondin 1 / RSPO1 Protein
    ¥580 - 25880