- ￥480 - 1480
- Sino Biological
- 北京
- 10605-HNAE
- 2026年01月26日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human EGF / Epidermal Growth Factor Protein
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/100.00 µg/500.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥1480.0 |
|---|---|---|---|
| 规格： | 100.00 µg | 产品价格： | ￥480.0 |
| 规格： | 500.00 µg | 产品价格： | ￥1080.0 |
重组人 EGF / Epidermal Growth Factor 蛋白（产品说明）
蛋白名称：Human EGF / Epidermal Growth Factor Protein
蛋白构建：A DNA sequence encoding the mature form of human EGF (NP_001954.2) (Asn971-Arg1023) was expressed and purified with an initial Met at the N-terminus.
表达宿主：E. coli
蛋白纯度：≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
蛋白活性：Measured in a cell proliferation assay using Balb/C 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.02-0.2ng/ml.
蛋白内毒素：< 5 EU per mg of the protein.
预测N端：Met
蛋白分子量：The recombinant human EGF consisting of 54 amino acids and has a calculated molecular mass of 6.35 kDa as estimated in SDS-PAGE under reducing conditions.
蛋白NP号：NP_001954.2
蛋白氨基酸序列：Asn971-Arg1023
蛋白标签：Native
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称：Human EGF / Epidermal Growth Factor Protein
蛋白构建：A DNA sequence encoding the mature form of human EGF (NP_001954.2) (Asn971-Arg1023) was expressed and purified with an initial Met at the N-terminus.
表达宿主：E. coli
蛋白纯度：≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
蛋白活性：Measured in a cell proliferation assay using Balb/C 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.02-0.2ng/ml.
蛋白内毒素：< 5 EU per mg of the protein.
预测N端：Met
蛋白分子量：The recombinant human EGF consisting of 54 amino acids and has a calculated molecular mass of 6.35 kDa as estimated in SDS-PAGE under reducing conditions.
蛋白NP号：NP_001954.2
蛋白氨基酸序列：Asn971-Arg1023
蛋白标签：Native
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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- 作者
- 内容
- 询问日期
文献和实验该产品被引用文献
1, Qiao, C; et al. PD173074 blocks G1/S transition via CUL3-mediated ubiquitin protease in HepG2 and Hep3B cells. PloS one, PMID: 32555680
2, Zhang, YL; et al. Chromatin complexes subunit BAP18 promotes triple-negative breast cancer progression through transcriptional activation of oncogene S100A9. Cell death & disease, PMID: 35484101
3, Bao, F; et al. Mitolysosome exocytosis, a mitophagy-independent mitochondrial quality control in flunarizine-induced parkinsonism-like symptoms. Science advances, PMID: 35417232
4, Chi, F; et al. TRG1
6, targeted by miR-76
5, inhibits breast cancer stem cell-like properties via regulating the NF-κB pathway. Molecular and cellular biochemistry, PMID: 35648115
5, Schiro, LE; et al. Isolation and comparison of neural stem cells from the adult rat brain and spinal cord canonical neurogenic niches. STAR protocols, PMID: 35693206
6, Lv, X; et al. JUN activation modulates chromatin accessibility to drive TNFα-induced mesenchymal transition in glioblastoma. Journal of cellular and molecular medicine, PMID: 35851726
7, Deng, H; et al. A fluorogenic probe for predicting treatment response in non-small cell lung cancer with EGFR-activating mutations. Nature communications, PMID: 36376325
8, Zhang, Z; et al. A drug screening to identify novel combinatorial strategies for boosting cancer immunotherapy efficacy. Journal of translational medicine, PMID: 36635683
9, Li, Y; et al. Lysine methylation promotes NFAT5 activation and determines temozolomide efficacy in glioblastoma. Nature communications, PMID: 37429858
10, Lee, KL; et al. Sustaining the Activation of EGFR Signal by Inflammatory Cytokine IL17A Prompts Cell Proliferation and EGFR-TKI Resistance in Lung Cancer. Cancers, PMID: 37444399
11, Sheng, Z; et al. SUMOylation of AnxA6 facilitates EGFR-PKCα complex formation to suppress epithelial cancer growth. Cell communication and signaling : CCS, PMID: 37528485 1
2, Ye, J; et al. TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling. Cell death discovery, PMID: 37845209 1
3, Kim, Y; et al. Cholesterol-dependent homeostatic regulation of very long chain sphingolipid synthesis. The Journal of cell biology, PMID: 37787764 1
4, Sun, C; et al. TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport. International journal of biological macromolecules, PMID: 38354922 1
5, Cao, L; et al. A LATS2 and ALKBH5 positive feedback loop supports their oncogenic roles. Cell reports, PMID: 38568805 1
6, Liu, X; et al. STAU1-mediated CNBP mRNA degradation by LINC00665 alters stem cell characteristics in ovarian cancer. Biology direct, PMID: 39080743 1
7, Hu, X; et al. Establishing patient-derived tumor organoids of bone metastasis from lung adenocarcinoma reveals the transcriptomic changes underlying denosumab treatment. Clinical & experimental metastasis, PMID: 39739069 1
8, Cuan, X; et al. Network Pharmacology Approach and Experimental Verification to Explore the Anti-NSCLC Mechanism of Grifolic Acid. International Journal of Molecular Sciences, PMID: 39859343 1
9, Zhu, Y; et al. CPT1A-mediated MFF succinylation promotes stemness maintenance in ovarian cancer stem cells. Communications biology, PMID: 39956875
20, Luo, J; et al. [Differential Characteristics of Human Airway Organoids at Different Stages of Differentiation After Respiratory Syncytial Virus Infection]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, PMID: 40599284
21, Zhou, L; et al. Glucose restriction induces degeneration of neurons with mitochondrial DNA depletion by altering ER-mitochondria calcium transfer. Molecular psychiatry, PMID: 40461815 2
2, Tang, F; et al. A chimeric oncolytic adenovirus carried by macrophages for glioma immunotherapy. Biochemical and biophysical research communications, PMID: 41191987
2, Zhang, YL; et al. Chromatin complexes subunit BAP18 promotes triple-negative breast cancer progression through transcriptional activation of oncogene S100A9. Cell death & disease, PMID: 35484101
3, Bao, F; et al. Mitolysosome exocytosis, a mitophagy-independent mitochondrial quality control in flunarizine-induced parkinsonism-like symptoms. Science advances, PMID: 35417232
4, Chi, F; et al. TRG1
6, targeted by miR-76
5, inhibits breast cancer stem cell-like properties via regulating the NF-κB pathway. Molecular and cellular biochemistry, PMID: 35648115
5, Schiro, LE; et al. Isolation and comparison of neural stem cells from the adult rat brain and spinal cord canonical neurogenic niches. STAR protocols, PMID: 35693206
6, Lv, X; et al. JUN activation modulates chromatin accessibility to drive TNFα-induced mesenchymal transition in glioblastoma. Journal of cellular and molecular medicine, PMID: 35851726
7, Deng, H; et al. A fluorogenic probe for predicting treatment response in non-small cell lung cancer with EGFR-activating mutations. Nature communications, PMID: 36376325
8, Zhang, Z; et al. A drug screening to identify novel combinatorial strategies for boosting cancer immunotherapy efficacy. Journal of translational medicine, PMID: 36635683
9, Li, Y; et al. Lysine methylation promotes NFAT5 activation and determines temozolomide efficacy in glioblastoma. Nature communications, PMID: 37429858
10, Lee, KL; et al. Sustaining the Activation of EGFR Signal by Inflammatory Cytokine IL17A Prompts Cell Proliferation and EGFR-TKI Resistance in Lung Cancer. Cancers, PMID: 37444399
11, Sheng, Z; et al. SUMOylation of AnxA6 facilitates EGFR-PKCα complex formation to suppress epithelial cancer growth. Cell communication and signaling : CCS, PMID: 37528485 1
2, Ye, J; et al. TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling. Cell death discovery, PMID: 37845209 1
3, Kim, Y; et al. Cholesterol-dependent homeostatic regulation of very long chain sphingolipid synthesis. The Journal of cell biology, PMID: 37787764 1
4, Sun, C; et al. TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport. International journal of biological macromolecules, PMID: 38354922 1
5, Cao, L; et al. A LATS2 and ALKBH5 positive feedback loop supports their oncogenic roles. Cell reports, PMID: 38568805 1
6, Liu, X; et al. STAU1-mediated CNBP mRNA degradation by LINC00665 alters stem cell characteristics in ovarian cancer. Biology direct, PMID: 39080743 1
7, Hu, X; et al. Establishing patient-derived tumor organoids of bone metastasis from lung adenocarcinoma reveals the transcriptomic changes underlying denosumab treatment. Clinical & experimental metastasis, PMID: 39739069 1
8, Cuan, X; et al. Network Pharmacology Approach and Experimental Verification to Explore the Anti-NSCLC Mechanism of Grifolic Acid. International Journal of Molecular Sciences, PMID: 39859343 1
9, Zhu, Y; et al. CPT1A-mediated MFF succinylation promotes stemness maintenance in ovarian cancer stem cells. Communications biology, PMID: 39956875
20, Luo, J; et al. [Differential Characteristics of Human Airway Organoids at Different Stages of Differentiation After Respiratory Syncytial Virus Infection]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, PMID: 40599284
21, Zhou, L; et al. Glucose restriction induces degeneration of neurons with mitochondrial DNA depletion by altering ER-mitochondria calcium transfer. Molecular psychiatry, PMID: 40461815 2
2, Tang, F; et al. A chimeric oncolytic adenovirus carried by macrophages for glioma immunotherapy. Biochemical and biophysical research communications, PMID: 41191987
相关实验
表皮生长因子(epidermal growth factor, EGF)
表皮生长因子是一种小肽,由53个氨基酸残基组成, 是类EGF大家族的一个成员。EGF同应答细胞表面的特异受体结合,一旦结合,便促进受体二聚化并使细胞质位点磷酸化。被激活的受体至少可与5种具有不同信号序列的蛋白结合,进行信号转导。EGF能够广泛促进细胞的增殖。
Regulator of Epidermal Growth Factor Signaling: Sprouty
Sprouty was first discovered through its downregulatory effect on fibroblast growth factor (FGF) receptor pathway during tracheal development. Sprouty expression is also induced by the epidermal growth factor receptor (EGFR) cascade
Semiquantitative immunoblots of membrane protein-epidermal growth factor
Membrane proteins or cytokines are sometimes difficult to isolate and purify. Our group recently concentrated on epidermal growth factor (EGF) protein expression studies. Mature EGF was initially identified from mouse submaxillary gland extract
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重组人 EGF / Epidermal Growth Factor蛋白
￥480 - 1480
