- ￥480 - 1480
- Sino Biological
- 北京
- 10605-HNAE
- 2025年08月12日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human EGF / Epidermal Growth Factor Protein
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/100.00 µg/500.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥1480.0 |
|---|---|---|---|
| 规格： | 100.00 µg | 产品价格： | ￥480.0 |
| 规格： | 500.00 µg | 产品价格： | ￥1080.0 |
重组人 EGF / Epidermal Growth Factor 蛋白（产品说明）
蛋白名称：Human EGF / Epidermal Growth Factor Protein
蛋白构建：A DNA sequence encoding the mature form of human EGF (NP_001954.2) (Asn971-Arg1023) was expressed and purified with an initial Met at the N-terminus.
表达宿主：E. coli
蛋白纯度：≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
蛋白活性：Measured in a cell proliferation assay using Balb/C 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.02-0.2ng/ml.
蛋白内毒素：< 5 EU per mg of the protein.
预测N端：Met
蛋白分子量：The recombinant human EGF consisting of 54 amino acids and has a calculated molecular mass of 6.35 kDa as estimated in SDS-PAGE under reducing conditions.
蛋白NP号：NP_001954.2
蛋白氨基酸序列：Asn971-Arg1023
蛋白标签：Native
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称：Human EGF / Epidermal Growth Factor Protein
蛋白构建：A DNA sequence encoding the mature form of human EGF (NP_001954.2) (Asn971-Arg1023) was expressed and purified with an initial Met at the N-terminus.
表达宿主：E. coli
蛋白纯度：≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
蛋白活性：Measured in a cell proliferation assay using Balb/C 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.02-0.2ng/ml.
蛋白内毒素：< 5 EU per mg of the protein.
预测N端：Met
蛋白分子量：The recombinant human EGF consisting of 54 amino acids and has a calculated molecular mass of 6.35 kDa as estimated in SDS-PAGE under reducing conditions.
蛋白NP号：NP_001954.2
蛋白氨基酸序列：Asn971-Arg1023
蛋白标签：Native
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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- 作者
- 内容
- 询问日期
文献和实验该产品被引用文献
1, Qiao C, et al. PD173074 blocks G1/S transition via CUL3-mediated ubiquitin protease in HepG2 and Hep3B cells.PloS one, PubMed ID: 32555680
2, Zhang YL, et al. Chromatin complexes subunit BAP18 promotes triple-negative breast cancer progression through transcriptional activation of oncogene S100A9.Cell death & disease, PubMed ID: 35484101
3, Bao F, et al. Mitolysosome exocytosis, a mitophagy-independent mitochondrial quality control in flunarizine-induced parkinsonism-like symptoms.Science advances, PubMed ID: 35417232
4, Chi F, et al. TRG16, targeted by miR-765, inhibits breast cancer stem cell-like properties via regulating the NF-κB pathway.Molecular and cellular biochemistry, PubMed ID: 35648115
5, Schiro LE, et al. Isolation and comparison of neural stem cells from the adult rat brain and spinal cord canonical neurogenic niches.STAR protocols, PubMed ID: 35693206
6, Lv X, et al. JUN activation modulates chromatin accessibility to drive TNFα-induced mesenchymal transition in glioblastoma.Journal of cellular and molecular medicine, PubMed ID: 35851726
7, Deng H, et al. A fluorogenic probe for predicting treatment response in non-small cell lung cancer with EGFR-activating mutations.Nature communications, PubMed ID: 36376325
8, Zhang Z, et al. A drug screening to identify novel combinatorial strategies for boosting cancer immunotherapy efficacy.Journal of translational medicine, PubMed ID: 36635683
9, Li Y, et al. Lysine methylation promotes NFAT5 activation and determines temozolomide efficacy in glioblastoma.Nature communications, PubMed ID: 37429858
10, Lee KL, et al. Sustaining the Activation of EGFR Signal by Inflammatory Cytokine IL17A Prompts Cell Proliferation and EGFR-TKI Resistance in Lung Cancer.Cancers, PubMed ID: 37444399
11, Sheng Z, et al. SUMOylation of AnxA6 facilitates EGFR-PKCα complex formation to suppress epithelial cancer growth.Cell communication and signaling : CCS, PubMed ID: 37528485
12, Ye J, et al. TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling.Cell death discovery, PubMed ID: 37845209
13, Kim Y, et al. Cholesterol-dependent homeostatic regulation of very long chain sphingolipid synthesis.The Journal of cell biology, PubMed ID: 37787764
14, Sun C, et al. TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport.International journal of biological macromolecules, PubMed ID: 38354922
15, Cao L, et al. A LATS2 and ALKBH5 positive feedback loop supports their oncogenic roles.Cell reports, PubMed ID: 38568805
16, Liu X, et al. STAU1-mediated CNBP mRNA degradation by LINC00665 alters stem cell characteristics in ovarian cancer.Biology direct, PubMed ID: 39080743
2, Zhang YL, et al. Chromatin complexes subunit BAP18 promotes triple-negative breast cancer progression through transcriptional activation of oncogene S100A9.Cell death & disease, PubMed ID: 35484101
3, Bao F, et al. Mitolysosome exocytosis, a mitophagy-independent mitochondrial quality control in flunarizine-induced parkinsonism-like symptoms.Science advances, PubMed ID: 35417232
4, Chi F, et al. TRG16, targeted by miR-765, inhibits breast cancer stem cell-like properties via regulating the NF-κB pathway.Molecular and cellular biochemistry, PubMed ID: 35648115
5, Schiro LE, et al. Isolation and comparison of neural stem cells from the adult rat brain and spinal cord canonical neurogenic niches.STAR protocols, PubMed ID: 35693206
6, Lv X, et al. JUN activation modulates chromatin accessibility to drive TNFα-induced mesenchymal transition in glioblastoma.Journal of cellular and molecular medicine, PubMed ID: 35851726
7, Deng H, et al. A fluorogenic probe for predicting treatment response in non-small cell lung cancer with EGFR-activating mutations.Nature communications, PubMed ID: 36376325
8, Zhang Z, et al. A drug screening to identify novel combinatorial strategies for boosting cancer immunotherapy efficacy.Journal of translational medicine, PubMed ID: 36635683
9, Li Y, et al. Lysine methylation promotes NFAT5 activation and determines temozolomide efficacy in glioblastoma.Nature communications, PubMed ID: 37429858
10, Lee KL, et al. Sustaining the Activation of EGFR Signal by Inflammatory Cytokine IL17A Prompts Cell Proliferation and EGFR-TKI Resistance in Lung Cancer.Cancers, PubMed ID: 37444399
11, Sheng Z, et al. SUMOylation of AnxA6 facilitates EGFR-PKCα complex formation to suppress epithelial cancer growth.Cell communication and signaling : CCS, PubMed ID: 37528485
12, Ye J, et al. TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling.Cell death discovery, PubMed ID: 37845209
13, Kim Y, et al. Cholesterol-dependent homeostatic regulation of very long chain sphingolipid synthesis.The Journal of cell biology, PubMed ID: 37787764
14, Sun C, et al. TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport.International journal of biological macromolecules, PubMed ID: 38354922
15, Cao L, et al. A LATS2 and ALKBH5 positive feedback loop supports their oncogenic roles.Cell reports, PubMed ID: 38568805
16, Liu X, et al. STAU1-mediated CNBP mRNA degradation by LINC00665 alters stem cell characteristics in ovarian cancer.Biology direct, PubMed ID: 39080743
相关实验
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表皮生长因子(epidermal growth factor, EGF)
表皮生长因子是一种小肽,由53个氨基酸残基组成, 是类EGF大家族的一个成员。EGF同应答细胞表面的特异受体结合,一旦结合,便促进受体二聚化并使细胞质位点磷酸化。被激活的受体至少可与5种具有不同信号序列的蛋白结合,进行信号转导。EGF能够广泛促进细胞的增殖。
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EGF重组蛋白|Recombinant Human EGF / Epidermal Growth Factor Protein
￥480 - 1480
