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| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-11598R |
| 英文名称 | AVPR1A Rabbit pAb |
| 中文名称 | 抗利尿激素1A抗体 |
| 英文别名 | AVP Receptor V1a; Antidiuretic hormone receptor 1A; Arginine vasopressin receptor 1A; AVPR 1; AVPR 1A; AVPR V1a; AVPR1; AVPR1A; SCCL vasopressin subtype 1a receptor; V1 vascular vasopressin receptor AVPR1A; V1a vasopressin receptor; V1aR; V1AR_HUMAN; Vascular/hepatic type arginine vasopressin receptor; Vascular/hepatic-type arginine vasopressin receptor; Vasopressin V1a receptor. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human AVP Receptor V1a |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 47 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurology process > Neuroendocrinology > Oxytocin & Vasopressin Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Vasopressin receptor Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. |
| 功能 | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验[IF={{ 4.4 }}] {Garrett A Enten. et al. Chemokine receptor hetero-oligomers regulate monocyte chemotaxis. LIFE SCI ALLIANCE. 2024 Aug;7(8):e202402657} {IF} {Human}
[IF={{ 3.48 }}] {Albee et al. Identification and functional characterization of arginine vasopressin receptor 1A : atypical chemokine receptor 3 heteromers in vascular smooth muscle. (2018) Open.Biol. 8} {ICC,CoIP,WB,FCM} {Human}
[IF={{ 3.24 }}] {Lauren J. Albee. et al. Plasticity of seven-transmembrane-helix receptor heteromers in human vascular smooth muscle cells. Plos One. 2021 Jun;16(6):e0253821} {Other} {}
[IF={{ 14.415 }}] {Yongli Shan. et al. Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony. Neuron. 2020 Oct;108:164} {IF,ICC} {Mouse}
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