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SLC40A1 | FPN1 Rabbit pAb(bs-4

906R)-50ul/100ul/200ul

价格￥1180 - 2800

品牌Bioss
货号bs-4906R
更新日期2026年10月13日

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规格：
50ul/100ul/200ul

规格：	50ul	产品价格：	￥1180.0
规格：	100ul	产品价格：	￥1980.0
规格：	200ul	产品价格：	￥2800.0

产品编号	bs-4906R
英文名称	SLC40A1 Rabbit pAb
中文名称	细胞膜铁转运蛋白FP1抗体
英文别名	Ferroportin 1; Ferroportin-1; FPN1; HFE4; IREG1; Iron regulated transporter 1; Iron-regulated transporter 1; MTP1; S40A1_HUMAN; SLC40A1; Solute carrier family 40 member 1; MST079; MSTP079; MTP1; SLC11A3.
产品应用	WB=1:500-2000 Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
交叉反应	Human (Mouse, Rat, Dog, Pig, Rabbit)
抗体来源	Rabbit
免疫原	KLH conjugated synthetic peptide derived from human SLC40A1/FPN1
亚型	IgG
性状	Liquid
纯化方法	affinity purified by Protein A
克隆类型	Polyclonal
理论分子量	63 kDa
浓度	1mg/ml
储存液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域	Metabolism > Pathways and Processes > Cofactors, Vitamins / minerals > Vitamins / minerals Signal Transduction > Metabolism > Vitamins / Minerals
亚基	Belongs to the S1LC40A transporter family._x000D_
亚细胞定位	Cell membrane; Multi-pass membrane protein. Note=Localized to the basolateral membrane of polarized epithelial cells.
组织特异性	Expressed in placenta, intestine, muscle and spleen.
相似性	Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
功能	May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).
保存条件	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料	SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.

应用	推荐稀释比例
{WB}	{1:500-2000}

Sample:
_x000D_ K562 (Human) Cell Lysate at 30 ug
_x000D_ HepG2 (Human) Cell Lysate at 30 ug
_x000D_ Primary: Anti-SLC40A1 (bs-4906R) at 1/1000 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 63 kD
_x000D_ Observed band size: 63 kD
_x000D_

Sample:
_x000D_ A673(Human) Cell Lysate at 30 ug
_x000D_ Primary: Anti-SLC40A1 (bs-4906R) at 1/1000 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 63 kD
_x000D_ Observed band size: 65 kD

Sample:
_x000D_ Lane 1: Human Hepg2 cell lysates
_x000D_ Lane 2: Human K562 cell lysates
_x000D_ Lane 3: Human Molt-4 cell lysates
_x000D_ Lane 4: Human Jurkat cell lysates
_x000D_ Primary: Anti-SLC40A1 (bs-4906R) at 1/1000 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 63 kDa
_x000D_ Observed band size: 60 kDa

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