Tissue/cell: rat lung tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-CC16/CCSP Polyclonal Antibody, Unconjugated(bs-1487R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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- bs-1487R
- 2025年10月16日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-1487R |
| 英文名称 | Uteroglobin Rabbit pAb |
| 中文名称 | 克拉拉细胞蛋白抗体 |
| 英文别名 | Clara cell protein 16; SCGB1A1; CC10; CCPBP; CCSP; UGB; UP-1; UP1; Secretoglobin, family 1A, member 1; PCB-binding protein; PCB-BP; UG; Clara cell phospholipid-binding; CC16; Clara cells 10 kDa secretory protein; Urinary protein 1; Urine protein 1; UTER_HUMAN; UTER_MOUSE; SCGB1A1. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Rat (Mouse) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse Uteroglobin |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 8.4 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Immunoglobulins > Class Switching |
| 亚基 | Homodimer; antiparallel disulfide-linked. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways). |
| 相似性 | Belongs to the secretoglobin family. |
| 功能 | Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq]. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验该产品被引用文献
[IF={{ 5.923 }}] {Mohamed Elbadawy. et al. Establishment of Intestinal Organoid from Rousettus leschenaultii and the Susceptibility to Bat-Associated Viruses, SARS-CoV-2 and Pteropine Orthoreovirus. Int J Mol Sci. 2021 Jan;22(19):10763} {IHC} {Bat}
[IF={{ 3.8 }}] {Mohamed Elbadawy. et al.Establishment of a bat lung organoid culture model for studying bat-derived infectious diseases.SCIENTIFIC REPORTS.2025 Feb 3;15(1):4035.} {IHC, IF} {}
[IF={{ 3.12 }}] {Mori, Gentaro, et al. "The genes Scgb1a1, Lpo and Gbp2 characteristically expressed in peri‐implant epithelium of rats." Clinical Oral Implants Research (2015).} {IHC} {="Rat"}
[IF={{ 11.864 }}] {Shibata T et al. Respiratory syncytial virus infection exacerbates pneumococcal pneumonia via Gas6/Axl-mediated macrophage polarization. J Clin Invest. 2020 Jun 1;130(6):3021-3037.} {IHC} {Mouse}
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were visualized by immunoblotting with rabbit specific anti‐murine apoAI followed by radiolabeled protein A. The nontransgenic control mouse plasma contains predominantly particles with α mobility (2A), while in contrast, plasma from the apoAI transgenic mice
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Uteroglobin Rabbit pAb(bs-1487R)-50ul/100ul/200ul
￥1180 - 2800
