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CD63 Rabbit pAb(bs-1523R)-50ul

/100ul/200ul

价格￥1180 - 2800

品牌Bioss
货号bs-1523R
更新日期2025年10月16日

应用范围产品信息以Bioss网站为准

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应用范围：
产品信息以Bioss网站为准
规格：
50ul/100ul/200ul

规格：	50ul	产品价格：	￥1180.0
规格：	100ul	产品价格：	￥1980.0
规格：	200ul	产品价格：	￥2800.0

产品编号	bs-1523R
英文名称	CD63 Rabbit pAb
中文名称	黑色素瘤相关抗原抗体
英文别名	Lysosomal associated membrane protein 3; CD63 antigen; CD63 antigen melanoma 1 antigen; CD63 molecule; granulophysin; LAMP 3; LAMP3; lysosome associated membrane glycoprotein 3; CD 63; CD63 antigen(melanoma 1 antigen); CD63_HUMAN; gp55; granulophysin; LAMP-3; LIMP; Lysosomal-associated membrane protein 3; Melanoma-associated antigen ME491; NGA; Ocular melanoma-associated antigen; PTLGP40; Tetraspanin-30; Tspan-30; Mast cell antigen AD1; ME491; melanoma 1 antigen; Melanoma associated antigen ME491; Melanoma associated antigen MLA1; MGC72893; MLA 1; MLA1; ocular melanoma associated antigen; OMA81H; Tetraspanin 30; Tspan 30; TSPAN30; Tumor biomarkers; Platelets markers.
产品应用	WB=1:500-2000 Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
交叉反应	Human
抗体来源	Rabbit
免疫原	KLH conjugated synthetic peptide derived from human CD63
亚型	IgG
性状	Liquid
纯化方法	affinity purified by Protein A
克隆类型	Polyclonal
理论分子量	26 kDa
实际分子量	30-50kDa
浓度	1mg/ml
储存液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域	Cancer > Invasion/microenvironment > ECM > Cell adhesion Cancer > Tumor biomarkers > Tumor antigens Cardiovascular > Blood > Platelets Immunology > Cell Type Markers > CD > Platelets Tags & Cell Markers > Cell Type Markers > Tumor Associated
亚细胞定位	Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Note=Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules.
组织特异性	Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.
相似性	Belongs to the tetraspanin (TM4SF) family.
功能	This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation.
保存条件	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]

应用	推荐稀释比例
{WB}	{1:500-2000}

25 ug total protein per lane of various lysates (see on figure) probed with CD63 polyclonal antibody, unconjugated (bs-1523R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

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