文献支持

FOXP3 | Scurfin Rabbit pAb(bs-

0269R)-50ul/100ul/200ul

价格￥1180 - 2800

品牌Bioss
货号bs-0269R
更新日期2026年10月13日

10 年钻石会员

详细信息
文献和实验
技术资料

规格：
50ul/100ul/200ul

规格：	50ul	产品价格：	￥1180.0
规格：	100ul	产品价格：	￥1980.0
规格：	200ul	产品价格：	￥2800.0

产品编号	bs-0269R
英文名称	FoxP3 Rabbit pAb
中文名称	叉头蛋白P3抗体
英文别名	Forkhead box protein P3; forkhead box P3; Scurfin; Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form; JM2; AIID; IPEX; PIDX; XPID; DIETER; FOXP3_HUMAN;
产品应用	WB=1:500-2000, IHC-P=1:200-1000, IHC-F=1:200-1000, IF=1:200-1000 Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
交叉反应	Mouse, Rat
抗体来源	Rabbit
免疫原	KLH conjugated synthetic peptide derived from human FoxP3
亚型	IgG
性状	Liquid
纯化方法	affinity purified by Protein A
克隆类型	Polyclonal
理论分子量	47 kDa
实际分子量	50-55kDa
浓度	1mg/ml
储存液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域	Cell Biology > Cell Cycle > Cell Division > Chromatid Cohesion Epigenetics and Nuclear Signaling > Transcription > Domain Families > Forkhead Box > FOXP Immunology > Adaptive Immunity > Regulatory T Cells
亚基	Interacts with IKZF3.
亚细胞定位	Nucleus (Potential).
翻译后修饰	Acetylation on lysine residues stabilizes FOXP3 and promotes differentiation of T-cells into induced regulatory T-cells (iTregs) associated with suppressive functions. Deacetylated by SIRT1.
相似性	Contains 1 C2H2-type zinc finger. Contains 1 fork-head DNA-binding domain.
功能	Probable transcription factor. Plays a critical role in the control of immune response.
保存条件	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料	The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

应用	推荐稀释比例
{WB}	{1:500-2000}
{IHC-P}	{1:200-1000}
{IHC-F}	{1:200-1000}
{IF}	{1:200-1000}

P‌‌araformaldehyde-fixed, paraffin embedded Mouse Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with FoxP3 Polyclonal Antibody, Unconjugated (bs-0269R) at 1:1000 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.

P‌‌araformaldehyde-fixed, paraffin embedded Mouse Thymus; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with FoxP3 Polyclonal Antibody, Unconjugated (bs-0269R) at 1:1000 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.

P‌‌araformaldehyde-fixed, paraffin embedded Rat Thymus; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with FoxP3 Polyclonal Antibody, Unconjugated (bs-0269R) at 1:1000 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.

25 ug total protein per lane of various lysates (see on figure) probed with FoxP3 polyclonal antibody, unconjugated (bs-0269R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。