ICAM1 Rabbit pAb(bs-0608R)-50ul/100ul/200ul
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ICAM1 Rabbit pAb(bs-0608R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-0608R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-0608R
    英文名称ICAM1 Rabbit pAb
    中文名称细胞间粘附分子-1(CD54)抗体
    英文别名BB2; CD54 antigen; ICAM 1; ICAM-1; Cell surface glycoprotein P3.58; Human rhinovirus receptor; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA2; MyD10; P3.58; Surface antigen of activated B cells; ICAM1_HUMAN; MALA-2; MyD10; intercellular adhesion molecule 1 precursor; intercellular adhesion molecule 1(CD54), human rhinovirus receptor; major group rhinovirus receptor.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CD54
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量56 kDa
    实际分子量58/100kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Angiogenesis > Endothelial Cell Markers

    Cardiovascular > Atherosclerosis > Vascular Inflammation > Leukocyte recruitment > Cell adhesion molecules

    Immunology > Adaptive Immunity > Regulatory T Cells

    Immunology > Cell Type Markers > CD > Adhesion

    Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus

    Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage

    Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage

    亚基 Homodimer (Probable). Interacts with human herpesvirus 8 MIR2 protein (Probable). Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with ARHGEF26/SGEF. Binds to coxsackievirus A21 capsid proteins and acts as a receptor for this virus.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    翻译后修饰Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
    相似性Belongs to the immunoglobulin superfamily. ICAM family.
    ontains 5 Ig-like C2-type (immunoglobulin-like) domains.
    功能 ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008].

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}
    {WB}{1:500-2000}

     

    ICAM1 Rabbit pAb(bs-0608R)-50u
    P‌‌araformaldehyde-fixed, paraffin embedded Human Lung Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ICAM1 Polyclonal Antibody, Unconjugated (bs-0608R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
    ICAM1 Rabbit pAb(bs-0608R)-50u
    P‌‌araformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ICAM1 Polyclonal Antibody, Unconjugated (bs-0608R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
    ICAM1 Rabbit pAb(bs-0608R)-50u
    P‌‌araformaldehyde-fixed, paraffin embedded Human Prostate Tumor; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ICAM1 Polyclonal Antibody, Unconjugated (bs-0608R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
    ICAM1 Rabbit pAb(bs-0608R)-50u
    P‌‌araformaldehyde-fixed, paraffin embedded Human Tonsil; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ICAM1 Polyclonal Antibody, Unconjugated (bs-0608R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
    ICAM1 Rabbit pAb(bs-0608R)-50u
    P‌‌araformaldehyde-fixed, paraffin embedded Human Lung; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ICAM1 Polyclonal Antibody, Unconjugated (bs-0608R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
    ICAM1 Rabbit pAb(bs-0608R)-50u
    P‌‌araformaldehyde-fixed, paraffin embedded Human Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ICAM1 Polyclonal Antibody, Unconjugated (bs-0608R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
    ICAM1 Rabbit pAb(bs-0608R)-50u
    P‌‌araformaldehyde-fixed, paraffin embedded Human Uterine body cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ICAM1 Polyclonal Antibody, Unconjugated (bs-0608R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
    ICAM1 Rabbit pAb(bs-0608R)-50u
    25 ug total protein per lane of various lysates (see on figure) probed with ICAM1 polyclonal antibody, unconjugated (bs-0608R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

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    该产品被引用文献

    [IF={{ 7.901 }}] {Shim W et al. Catechin solubilization by spontaneous hydrogen bonding with poly(ethylene glycol) for dry eyetherapeutics. J Control Release. 2019 May 20.} {IHC} {Mouse}

    [IF={{ 7.5 }}] {Xiangke Ma. et al. Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation through inhibiting COX-2. BIOMED PHARMACOTHER. 2023 Nov;167:115501} {WB} {Mouse,Human}

    [IF={{ 6.7 }}] {Lijuan Shi. et al. Vascularized characteristics and functional regeneration of three-dimensional cell reconstruction of oral mucosa equivalents based on vascular homeostasis phenotypic modification. J TISSUE ENG. ;():} {WB} {Human}

    [IF={{ 5.201 }}] {Qian Liet al. LOX-1 Regulates P. gingivalis-Induced Monocyte Migration and Adhesion to Human Umbilical Vein Endothelial Cells. Front Cell Dev Biol . 2020 Jul 14;8:596.} {WB} {Human}

    [IF={{ 4.9 }}] {Mey-Fann Lee. et al. The Anti-Inflammatory Effect of Lactococcus lactis-Ling-Zhi 8 on Ameliorating Atherosclerosis and Nonalcoholic Fatty Liver in High-Fat Diet Rabbits. INT J MOL SCI. 2024 Jan;25(20):11278} {IHC} {Rabbit}

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    ICAM1 Rabbit pAb(bs-0608R)-50ul/100ul/200ul
    ¥1180 - 2800