- 询价
- Signalway Antibody
- 11328
- USA
- 2025年07月08日
- WB
- Rabbit
- Hu Ms Rt
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- 详细信息
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- 文献和实验
- 技术资料
- 抗体英文名：
TrkB(Phospho-Tyr705) Antibody
- 靶点：
TrkB
- 浓度：
1.0mg/ml
- 应用范围：
WB
- 宿主：
Rabbit
- 适应物种：
Hu Ms Rt
- 克隆性：
Polyclonal
- 保存条件：
Store at -20℃
- 形态：
liquid
- 免疫原：
Peptide sequence around phosphorylation site of tyrosine 705 (T-D-Y P-Y-R) derived from Human TrkB.
Purification：
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Specificity：
The antibody detects endogenous level of TrkB only when phosphorylated at tyrosine 706.
Immunogen Description：
Peptide sequence around phosphorylation site of tyrosine 706 (T-D-Y P-Y-R) derived from Human TrkB.
Target Name：TrkB
Modification：Phospho
Alternative Names：
BDNF/NT-3 growth factors receptor precursor; EC 2.7.10.1; GP145-TrkB; GP145-TrkB/GP95-TrkB; NTRK2
Accession No. ：
Swiss-Prot: Q16620
NCBI Protein: NP _001007098.1
Concentration： 1.0mg/ml
Formulation：
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Images:
Western blot analysis of extracts from mouse brain tissue using TrkB(Phospho-Tyr706) Antibody #11328 and the same antibody preincubated with blocking peptide.
产品详细信息请点击：TrkB(Phospho-Tyr705) Antibody
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文献和实验PMID: 30127743
Sex-Dependent Effects of Environmental Enrichment on Spatial Memory and Brain-Derived Neurotrophic Factor (BDNF) Signaling in a Developmental Two-Hit Mouse Model Combining BDNF Haploinsufficiency and Chronic Glucocorticoid Stimulation.In Front Behav Neurosci On 2018 Oct 9 by Adrienne M. Grech, Udani Ratnayake et al..PMID: 30356704, , (2018),
PMID: 30356704
Chronic Intermittent Hypobaric Hypoxia Pretreatment Ameliorates Ischemia-Induced Cognitive Dysfunction Through Activation of ERK1/2-CREB-BDNF Pathway in Anesthetized Mice.In Neurochem Res on 2017 Feb by Jintian Wang , Shixiao Zhang,et al..PMID: 27822668, , (2017),
PMID: 27822668
ERα Signaling Is Required for TrkB-Mediated Hippocampal Neuroprotection in Female Neonatal Mice after Hypoxic Ischemic Encephalopathy. In eNeuro on 2016 Jan 28 by Ulas Cikla, Vishal Chanana, et al..PMID: 26839918, , (2016),
PMID: 26839918
Sex‐dependent alterations in BDNF‐TrkB signaling in the hippocampus of reelin heterozygous mice: a role for sex steroid hormones.In J Neurochem on 2013 Aug by Rachel A Hill, Yee-Wen Candace Wu, et al..PMID:23414458
PMID: 23414458
A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease. In J Neurosci on 2013 Nov 27
by Tao Yang, Christina Condon, et al..PMID: 24285878
PMID: 24285878
Sex-specific and region-specific changes in BDNF–TrkB signalling in the hippocampus of 5-HT1A receptor and BDNF single and double mutant mice. In Brain Res
on 2012 May 3 by YeeWen Candace Wu, Rachel A Hill, et al..PMID:22464183
PMID:22464183
Sex-dependent and region-specific changes in TrkB signaling in BDNF heterozygous mice. In Brain Res on 2011 Apr 12 by Rachel A Hill, Maarten van den Buuse，
et al..PMID: 21281620
PMID: 21281620
A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth. In Neuropharmacology on 2016 Nov by Tao Yang, Stephen M Massa,et al..PMID:27334657
PMID:27334657
High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice. In Neurobiol Dis on 2014 Sep by Christina Mo, Terence Y Pang,et al..PMID:24825316
PMID:24825316
Long-term effects of combined neonatal and adolescent stress on brain-derived neurotrophic factor and dopamine receptor expression in the rat forebrain.In Biochim Biophys Acta on 2014 Nov by Rachel A Hill, Szerenke Kiss Von Soly ,et al..PMID:25159716
PMID:25159716
Sex‐specific disruptions in spatial memory and anhedonia in a “two hit” rat model correspond with alterations in hippocampal brain‐derived neurotrophic factor expression and signaling. In Hippocampus on 2014 Oct by Rachel A Hill, Maren Klug,et al..PMID:24802968
PMID:24802968
Brain-derived neurotrophic factor heterozygous mutant rats show selective cognitive changes and vulnerability to chronic corticosterone treatment. In Neuroscience on 2015 Jan 22 by A Gururajan, R A Hill,et al..PMID:25445195
PMID:25445195
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人酪氨酸激酶B (TrKB)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和尿液、唾液生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 TrKB/CCL5 单抗包被于酶标板上，标准品和样品中的 TrKB与单抗结合，加入生物
运用Cell Based Elisa检测信号通路蛋白和磷酸化蛋白
using Phospho-p38 antibody (A) and Total-p38 antibody (B). Cell Based Elisa were performed directly in the 96-well plates using Phospho-p38 and Total-p38 antibodies (C). Figure 3: JNK detection with FACECells were serum-starved for 16 hours
。所以，我们建议使用微波炉或高压锅加热煮沸以达到最佳抗原修复效果。抗体：Phospho–Stat3 (Tyr705)(D3A7) XP. Rabbit mAb #9145样本：石蜡包埋人类肺部肿瘤样本煮沸设备：浴锅 (左)，微波炉 (中)，高压锅 (右)免疫染色—封闭在 IHC–P 中，我们建议在室温下在含有 Tween20 的 TBST 缓冲液和 5% 正常山羊血清 (NGS) 中封闭样品，时长 1 小时，以防止非特异性背景染色。在进行 IHC–F 时，在含有 0.3% Triton. X–100 的 1X
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