产品封面图
研选

JNK1/JNK2/JNK3(phospho-Thr183/

Tyr185) Antibody
收藏
  • ¥2250
  • Signalway Antibody已认证
  • 11504
  • USA
  • 2025年07月16日
  • WB IF
  • Rabbit
  • Hu Ms Rt
快速发货
快速回复
售后服务
技术支持
文献支持
avatar
品牌商
15钻石会员
  • 企业认证

    点击 QQ 联系

    • 详细信息
    • 用户评价
    • 文献和实验
    • 技术资料
    • 抗体英文名

      JNK1/JNK2/JNK3(phospho-Thr183/Tyr185) Antibody

    • 靶点

      JNK1/JNK2/JNK3

    • 浓度

      1.0mg/ml

    • 应用范围

      WB IF

    • 宿主

      Rabbit

    • 适应物种

      Hu Ms Rt

    • 克隆性

      多克隆

    • 保存条件

      Store at -20℃

    • 形态

      liquid

    • 免疫原

      Peptide sequence around phosphorylation site of Thr183/Tyr185 (M-M-T(p)-P-Y(p)- V - V ) derived from Human JNK1/JNK2/JNK3.

    • 规格

      100ul

    Purification:
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

    Specificity:
    The antibody detects endogenous level of JNK1/JNK2/JNK3 only when phosphorylated at Thr183/Tyr185.

    Immunogen Type:Peptide-KLH

    Immunogen Description:
    Peptide sequence around phosphorylation site of Thr183/Tyr185 (M-M-T(p)-P-Y(p)- V - V ) derived from Human JNK1/JNK2/JNK3.

    Target Name:JNK1/JNK2/JNK3

    Modification:Phospho

    Alternative Names:
    Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; JNK-46

    Accession No.:
    Swiss-Prot: P45983 P45984 P53779
    NCBI Protein: NP_002741.1 NP_001128516.1 NP_002744.1

    Concentration: 1.0mg/ml

    Formulation :
    Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

    Images
    产品细节图片1
    Western blot analysis of extracts from C6 cells untreated or treated with anisomycin using JNK1/JNK2/JNK3(phospho-Thr183/Tyr185) Antibody #11504.
    产品细节图片2
    Immunofluorescence staining of methanol-fixed Hela cells using JNK1/JNK2/JNK3(phospho-Thr183/Tyr185) Antibody #11504.
    产品细节图片3
    Western blot analysis of extracts from 293 cells, treated with Anisomycin or calf intestinal phosphatase (CIP), using JNK1/JNK2/JNK3 (phospho-Thr183/Tyr185) Antibody #11504.

    产品详细信息请点击:JNK1/JNK2/JNK3(phospho-Thr183/Tyr185) Antibody

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标用户评价
      图标暂无用户评价
      图标文献和实验
      该产品被引用文献
      Persistent Wnt/β-catenIn signalIng In mouse epithelium Induces the ectopic Dspp expression In cheek mesenchyme. In Organogenesis on 2019 by Zhou N, Li N, et al..PMID:30570432, , (2019),
      PMID: 30570432

      Potential role of P2X7 receptor In neurodegenerative processes In a murIne model of glaucoma. In BraIn Res Bull on 2019 May 16 by P rez de Lara MJ, Avil s-Trigueros M, et al.. PMID: 31102752, , (2019),
      PMID: 31102752

      AesculIn protects agaInst DSS-Induced colitis though activatIng PPARγ and InhibitIng NF- B pathway. In Eur J Pharmacol on 2019 Aug 15 by Tian X, Peng Z,et al..PMID:31202807, , (2019),
      PMID: 31202807

      HMGN2 regulates non-tuberculous mycobacteria survival via modulation of M1 macrophage polarization. In J Cell Mol Med on 2019 Dec by Wang X, Chen S, et al..PMID:31596045, , (2019),
      PMID: 31596045

      Differential apoptosis gene expressions of rhabdomyosarcoma cells in response to enterovirus 71 infection.In BMC Infect Dis on 2012 Nov 28 by Shi W, Li X,et al..PMID:23191987
      PMID:23191987

      MK-2206 induces cell cycle arrest and apoptosis in HepG2 cells and sensitizes TRAIL-mediated cell death.In Mol Cell Biochem on 2013 Oct by Peng Jiao, Yun-Sheng Zhou,et al..PMID:23797319

      PMID:23797319

      Cardamonin Protects Septic Mice From Acute Lung Injury by Preventing Endothelial Barrier Dysfunction.In J Biochem Mol Toxicol on 2012  Jul by Zhifeng Wei, Jian Yang,et al..PMID:22696397
      PMID:22696397

      Effects of IL-1 receptor-associated kinase-4 gene silencing on human osteoblast-like cells. In Connect Tissue Res on 2012 by Zibo Yang, Baoding Huang, et al..PMID: 22606974
      PMID: 22606974


      Ellagic Acid Inhibits RANKL-induced Osteoclast Differentiation by Suppressing the p38 MAP Kinase Pathway.In Arch Pharm Res on 2017 Jan by Mpho Rantlha , Travers Sagar,et al..PMID: 27384064
      PMID: 27384064


      Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids From Khaya grandifoliola C.DC Protect L-02 Hepatocytes Against Acetaminophen-Induced Hepatotoxicity.In Front Pharmacol on 2017 Sep 19 by Arnaud F Kouam, Fei Yuan,et al..PMID: 28974930
      PMID: 28974930


      Inhibitory effects of eugenol on RANKL-induced osteoclast formation via attenuation of NF-κ B and MAPK pathways.In  Connect Tissue Res on 2015 Jun by Vishwa Deepak,AbeKasongaetal..PMID:25405641
      PMID:25405641


      Piperine alleviates osteoclast formation through the p38/c‐Fos/NFATc1 signaling axis.In  Biofactors on Nov-Dec 2015 by Vishwa Deepak , Marlena C Kruger et al..PMID: 26627060
      PMID: 26627060


      The Effects of Xiangqing Anodyne Spray on treating acute soft-Tissue injury mainly depend on suppressing activations of AKT and p38 pathways.In  Evid Based Complement Alternat Med on 2016 by Shudong Wang , Tao Li  et al..PMID:27190541
      PMID:27190541

      An alternatively spliced variant of CXCR3 mediates the metastasis of CD133+ liver cancer cells induced by CXCL9.In  Oncotarget on 2016 Mar 22 by Qiang Ding, Yujia Xia et al..PMID:26883105
      PMID:26883105


      Cannabinoid receptor agonist WIN55,212-2 and fatty acid amide hydrolase inhibitor URB597 suppress chronic cerebral hypoperfusion-induced neuronal apoptosis by inhibiting c-Jun N-terminal kinase signaling.In  Neuroscience 2015 Aug 20 by S-H Su  , Y-F Wu et al..PMID:25795598
      PMID:25795598


      Astragalus polysaccharides exerts anti-infective activity by inducing human cathelicidin antimicrobial peptide LL-37 in respiratory epithelial cells.In Phytother Res. On 2018 Aug by Zhao L, Tan S et al..PMID: 29672953
      PMID: 29672953

      Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation.In Pharm Biol. On 2018 Dec by Zhang H, Ren QC et al..PMID: 31070535 
      PMID: 31070535 


      The protective effects of β-sitosterol and vermicularIn from Thamnolia vermicularis (Sw.) Ach. agaInst skIn agIng In vitro.In An Acad Bras Cienc on 2019 Dec 2 by Haiyuan YU, Shen X,et al..PMID:31800700
      PMID:31800700







       
      相关实验
      • 运用Cell Based Elisa检测信号通路蛋白和磷酸化蛋白

        results of phosphorylated proteins磷酸化的试剂盒中的抗体是经过大量筛选,选取了高特异性和低背景的抗体。p-P38MAPK抗体是基于P38的磷酸化Thr180到Tyr182这个位点多肽片段所制备。P-JNK抗体是基于人的Thr183Tyr185.这个抗体可以同时识别P-JNK1和P-JNK2.我们在运用Cell Based Elisa P38和JNK两个试剂盒做检测的同时,又用传统的WB方式来验证这个结果。经过反复验证,都得出了同样的结果, Cell Based

      • 【求助】关于gsk3-beta功能的疑问

        ) is accompanied with or inactivates the GSK activity. However, it is still not conclusive what the role of Tyr phosphorylation (Y216 fro beta, Y279 for alpha) on GSK activity is. One reference is a review paper published in Cell in 2001, you may take a quick

      • L-02细胞系特性

        secondary antibody were purchased from GIBCO-BRL. Phosphospecific rabbit polyclonal antibodies against 180Thr and 182Tyr dual-phosphorylated p38, against total p38 (phosphorylation state independent), against 204Tyr-phosphorylated ERK1/2 and against total

      图标技术资料

      需要更多技术资料 索取更多技术资料

      资料下载:

      11504.pdf 附 (下载 2 次)

      研选
      JNK1/JNK2/JNK3(phospho-Thr183/Tyr185) Antibody
      ¥2250