- ￥750 - 24150
- Sino Biological
- 北京
- 10001-H08H
- 2025年08月12日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human EGFR / HER1 / ErbB1 Protein (His Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/10.00 µg/20.00 µg/100.00 µg/500.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥24150.0 |
|---|---|---|---|
| 规格： | 10.00 µg | 产品价格： | ￥750.0 |
| 规格： | 20.00 µg | 产品价格： | ￥1400.0 |
| 规格： | 100.00 µg | 产品价格： | ￥3870.0 |
| 规格： | 500.00 µg | 产品价格： | ￥15050.0 |
重组人 EGFR / HER1 / ErbB1 蛋白 (His标签)（产品说明）
蛋白名称：Human EGFR / HER1 / ErbB1 Protein (His Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Ser 645) of human EGFR (NP_005219) was expressed with a C-terminal polyhistidine tag.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：Measured by its binding ability in a functional ELISA. Immobilized Human EGF hFc (Cat: 10605-H01H) at 2 μg/ml (100 μl/well) can bind Human EGFR His (Cat: 10001-H08H), the EC50 of Human EGFR His is 100-500 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Leu 25
蛋白分子量：The recombinant human EGF receptor consists of 630 amino acids and has a calculated molecular mass of 69.8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 110 kDa protein in SDS-PAGE under reducing conditions.
蛋白NP号：NP_005219
蛋白氨基酸序列：Met1-Ser645
蛋白标签：C-His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称：Human EGFR / HER1 / ErbB1 Protein (His Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Ser 645) of human EGFR (NP_005219) was expressed with a C-terminal polyhistidine tag.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：Measured by its binding ability in a functional ELISA. Immobilized Human EGF hFc (Cat: 10605-H01H) at 2 μg/ml (100 μl/well) can bind Human EGFR His (Cat: 10001-H08H), the EC50 of Human EGFR His is 100-500 ng/mL.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Leu 25
蛋白分子量：The recombinant human EGF receptor consists of 630 amino acids and has a calculated molecular mass of 69.8 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 110 kDa protein in SDS-PAGE under reducing conditions.
蛋白NP号：NP_005219
蛋白氨基酸序列：Met1-Ser645
蛋白标签：C-His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验该产品被引用文献
1, Zhang J, et al. Phage-derived fully human antibody scFv fragment directed against human vascular endothelial growth factor receptor 2 blocked its interaction with VEGF.Biotechnology progress, PubMed ID: 22581629
2, Yao S, et al. Erbin interacts with c-Cbl and promotes tumourigenesis and tumour growth in colorectal cancer by preventing c-Cbl-mediated ubiquitination and down-regulation of EGFR.The Journal of pathology, PubMed ID: 25521828
3, Nagayasu M, et al. Combination of cassette-dosing and microsampling for reduced animal usage for antibody pharmacokinetics in cynomolgus monkeys, wild-type mice, and human FcRn transgenic mice.Pharmaceutical research, PubMed ID: 33782838
4, Saeed MEM, et al. In Silico and In Vitro Screening of 50 Curcumin Compounds as EGFR and NF-κB Inhibitors.International journal of molecular sciences, PubMed ID: 35409325
5, Yeh YH, et al. A molecular toolkit for heterologous protein secretion across Bacteroides species.bioRxiv : the preprint server for biology, PubMed ID: 38168418
2, Yao S, et al. Erbin interacts with c-Cbl and promotes tumourigenesis and tumour growth in colorectal cancer by preventing c-Cbl-mediated ubiquitination and down-regulation of EGFR.The Journal of pathology, PubMed ID: 25521828
3, Nagayasu M, et al. Combination of cassette-dosing and microsampling for reduced animal usage for antibody pharmacokinetics in cynomolgus monkeys, wild-type mice, and human FcRn transgenic mice.Pharmaceutical research, PubMed ID: 33782838
4, Saeed MEM, et al. In Silico and In Vitro Screening of 50 Curcumin Compounds as EGFR and NF-κB Inhibitors.International journal of molecular sciences, PubMed ID: 35409325
5, Yeh YH, et al. A molecular toolkit for heterologous protein secretion across Bacteroides species.bioRxiv : the preprint server for biology, PubMed ID: 38168418
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EGFR重组蛋白|Recombinant Human EGFR / HER1 / ErbB1 Protein (His Tag)
￥750 - 24150
