- ￥2130 - 13850
- Sino Biological
- 北京
- 10001-H02H
- 2025年08月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human EGFR / HER1 / ErbB1 Protein (Fc Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/50.00 µg/100.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥13850.0 |
|---|---|---|---|
| 规格： | 50.00 µg | 产品价格： | ￥2310.0 |
| 规格： | 100.00 µg | 产品价格： | ￥2130.0 |
重组人 EGFR / HER1 / ErbB1 蛋白 (Fc标签)（产品说明）
蛋白名称：Human EGFR / HER1 / ErbB1 Protein (Fc Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Ser 645) of human EGFR (NP_005219) was fused with the Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 97 % as determined by SDS-PAGE
蛋白活性：Measured by its binding ability in a functional ELISA. Immobilized recombinant human EGF at 10 μg/ml (100 μl/well) can bind human EGFR with a linear range of 0.64-400 ng/ml.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Leu 25
蛋白分子量：The recombinant human EGFR/Fc chimera is a homodimeric protein. The reduced monomer consists of 860 amino acids and has a calculated molecular mass of 95 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 110-140 kDa protein in SDS-PAGE under reducing conditions.
蛋白NP号：NP_005219
蛋白氨基酸序列：Met1-Ser645
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称：Human EGFR / HER1 / ErbB1 Protein (Fc Tag)
蛋白构建：A DNA sequence encoding the extracellular domain (Met 1-Ser 645) of human EGFR (NP_005219) was fused with the Fc region of human IgG1 at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 97 % as determined by SDS-PAGE
蛋白活性：Measured by its binding ability in a functional ELISA. Immobilized recombinant human EGF at 10 μg/ml (100 μl/well) can bind human EGFR with a linear range of 0.64-400 ng/ml.
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Leu 25
蛋白分子量：The recombinant human EGFR/Fc chimera is a homodimeric protein. The reduced monomer consists of 860 amino acids and has a calculated molecular mass of 95 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 110-140 kDa protein in SDS-PAGE under reducing conditions.
蛋白NP号：NP_005219
蛋白氨基酸序列：Met1-Ser645
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验该产品被引用文献
1, Alvarez-Cienfuegos A, et al. Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains.Scientific reports, PubMed ID: 27345490
2, Minkoff BB, et al. Plasma-Generated OH Radical Production for Analyzing Three-Dimensional Structure in Protein Therapeutics.Scientific reports, PubMed ID: 29021557
3, Ding X, et al. A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity.EBioMedicine, PubMed ID: 32950002
4, Kim HS, et al. Construction and Functionalization of a Clathrin Assembly for a Targeted Protein Delivery.Small (Weinheim an der Bergstrasse, Germany), PubMed ID: 36456203
5, Sakamoto H, et al. Development of tight junction-strengthening compounds using a high-throughput screening system to evaluate cell surface-localized claudin-1 in keratinocytes.Scientific reports, PubMed ID: 38332234
2, Minkoff BB, et al. Plasma-Generated OH Radical Production for Analyzing Three-Dimensional Structure in Protein Therapeutics.Scientific reports, PubMed ID: 29021557
3, Ding X, et al. A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity.EBioMedicine, PubMed ID: 32950002
4, Kim HS, et al. Construction and Functionalization of a Clathrin Assembly for a Targeted Protein Delivery.Small (Weinheim an der Bergstrasse, Germany), PubMed ID: 36456203
5, Sakamoto H, et al. Development of tight junction-strengthening compounds using a high-throughput screening system to evaluate cell surface-localized claudin-1 in keratinocytes.Scientific reports, PubMed ID: 38332234
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EGFR重组蛋白|Recombinant Human EGFR / HER1 / ErbB1 Protein (Fc Tag)
￥2130 - 13850
