抗人 CD369 (Dectin-1/CLEC7A) 荧光标

anti-human CD369 (Dectin-1/CLEC7A) Antibody-APC详细如下：

Description ：CD369 (Dectin-1), also known as CLEC7A and beta-glucan receptor (BGR), is a 33 kD type IItransmembrane C-type lectin. It consists of a C-terminal stalk with a carbohydrate recognitiondomain (CRD) in the extracellular domain, a transmembrane segment, and a short N-terminalITAM containing a cytoplasmic tail. CLEC7A is predominantly expressed on dendritic cells.Subsequent work has shown expression on B cells, monocytes, eosinophils, mast cells,macrophages, endothelial cells, and low expression on some subsets of T cells. CLEC7A lacksresidues involved in calcium ligation that mediates carbohydrate-binding by classical C-typelectins. CLEC7A functions as a receptor to mediate innate immunity to fungal pathogens byselectively binding beta-glucan polymers, a major component of yeast and mycobacterial cellwalls.

Verified Reactivity ：Human

Antibody Type ：Monoclonal

Host Species ：Mouse

Immunogen ：Ectodomain with C-term hFc fusion, RIBLS.

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation ：The antibody was purified by affinity chromatography and conjugated with APC under optimalconditions.

Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.

Application ：FC - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser ：Red Laser (633 nm)