- ￥500 - 1700
- 齐源
- 100201
- 国产/进口
- 2025年07月13日
- FC, IHC-F, IP, ICC
- 大鼠
- 小鼠
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD3
- 级别：
CD3 Antibody
- 目录编号：
CD3 Antibody
- 克隆性：
单克隆
- 抗原来源：
大鼠
- 保质期：
CD3 Antibody
- 抗体英文名：
Purified anti-mouse CD3 Antibody
- 抗体名：
CD3 Antibody
- 标记物：
CD3 Antibody
- 宿主：
大鼠
- 适应物种：
小鼠
- 免疫原：
CD3 Antibody
- 亚型：
CD3 Antibody
- 形态：
CD3 Antibody
- 应用范围：
FC, IHC-F, IP, ICC
- 保存条件：
2-8℃
- 浓度：
0.5 mg/ml
- 规格：
50 ug/500 ug
| 规格： | 50 ug | 产品价格： | ￥500.0 |
|---|---|---|---|
| 规格： | 500 ug | 产品价格： | ￥1700.0 |
Description ：CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells,NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composedof CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains.CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognitionby binding the peptide/MHC antigen complex
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Immunogen ：γδTCR-positive T-T hybridoma D1
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation ：The antibody was purified by affinity chromatography.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.
Application ：FC - Quality tested、IHC-F - Verified、IP, ICC - Reported in the literature, not verified in house
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per millioncells in 100 µl volume. For immunohistochemistry on frozen tissue sections, a concentration of 10µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for eachapplication.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验1. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations：
1. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
2. Pietras E, et al. 2016. Nat Cell Biol. 10.1038/ncb3346. PubMed
3. Abdel-Gadir A, et al. 2019. Nat Med. 25:1164. PubMed
4. Hamada T, et al. 2008. J Immunol. 180:1843. PubMed
5. Zhao J, et al. 2021. JCI Insight. 6:. PubMed
6. Gern BH, et al. 2021. Cell Host Microbe. 29(4):594-606.e6. PubMed
7. Kulkarni NN, et al. 2020. J Invest Dermatol. 140:645. PubMed
8. Boyd DF, et al. 2020. Nature. 587:466. PubMed
9. Xiao J, et al. 2012. Arterioscler Thromb Vasc Biol. 32:386. PubMed
10. Bergstrom K, et al. 2008. Infect Immun. 76:796. PubMed
11. Mazor R, et al. 2018. Proc Natl Acad Sci U S A. 115:E733. PubMed
12. Burrello C, et al. 2018. Front Med (Lausanne). 5:21. PubMed
【摘要】目的 构建和表达抗CD3/抗Pgp微型双功能抗体，并测定该微型双功能抗体的生物学活性。方法 采用PCR和overlap PCR方法构建抗CD3/抗CD20微型双功能抗体，并用双脱氧终止法测定DNA序列；采用亲和层析法纯化该产物，并用Western blot和分子排阻层析鉴定纯化产物；采用免疫荧光法、放射免疫分析法和玫瑰花环试验鉴定纯化产物与靶细胞的结合活性。结果 DNA序列测定结果表明：抗CD3/抗Pgp微型双功能抗体已构建成功，表达可溶性产物的产量达2mg/l以上，纯化产物中二
Maturation Changes in Purified Phagosomes
The amoeba Dictyostelium discoideum is an established model to study phagocytosis. The sequence of events leading to the internalization and degradation of a particle is conserved in D. discoideum compared to metazoan cells. As its small
Phage Display and Selections on Purified Antigens
31, 1998). In many case, the protein of interest, or a relevant portion of this protein such as its extracellular domain is available as purified protein. In such cases, phage display on purified antigen is an easy and fast way to select antibody
