- ￥4800
- Tanda
- 美国
- TD-26314
- 2025年10月28日
- ELISA, WB, IHC
- Mouse
- 脊椎动物
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide from the internal region of JAK2 which includes the mutation of R683G, human origin.
- 亚型：
lgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
单克隆
- 标记物：
FITC
- 适应物种：
脊椎动物
- 保质期：
24个月
- 抗原来源：
蛋白
- 目录编号：
TD-26314
- 级别：
科研级
- 库存：
999
- 供应商：
武汉天德
- 宿主：
Mouse
- 应用范围：
ELISA, WB, IHC
- 浓度：
0.5 mg/ml
- 靶点：
R683G
- 抗体英文名：
Anti JAK2(R683G) Mouse Monoclonal Antibody
- 抗体名：
JAK2(R683G)
- 规格：
100 μL
JAK2(R683G)
| Cat. #: TD-26314 |
| Size: 100 µL |
| Gene Symbol: JAK2, JTK10, THCYT3 |
| Description: Anti-JAK2(R683G) Mouse Monoclonal Antibody |
| Background: JAK2 is a non-receptor tyrosine kinase. It is a number of the Janus kinase family and has been implicated in signaling by members of the type II cytokine receptor family, the GM-CSF receptor family, the gp130 receptor family, and the single chain receptors. JAK2 orthologs have been identified in all mammals for which complete genome genome data are available. Mutations of JAK2 have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other myeloproliferative disorders. |
| Immunogen: A synthetic peptide from the internal region of JAK2 which includes the mutation of R683G, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 0.5 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes R683G mutant, but not wild type JAK2 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
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Immunofluorescence:
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文献和实验Recently, a point mutation in the JAK2 gene, JAK2 V617F , was discovered in several myeloid proliferative neoplasms including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). Demonstration
Methods for Detecting Mutations in the Human JAK2 Gene
Mutations in the JAK2 gene are prevalent in the human myeloid malignancies, being present in virtually all cases of polycythemia vera, and a significant proportion of patients with other myeloproliferative disorders. Various methods
人JAK2 酶联免疫分析（ ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中JAK2 的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中 人 JAK2 水平。用纯化的 人 JAK2 抗体 包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 JAK2 ，再与 HRP 标记的 JAK2 抗体结合，形成抗体 - 抗原 - 酶标抗体复合物，经过彻底洗涤后加底物
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