武汉天德生物科技有限公司

Predicted to enable RNA binding activity and RNA helicase activity. Acts upstream of or within germ cell development; gonad development; and regulation of meiotic cell cycle. Located in P granule. Is expressed in several structures, including blastodisc; germ line cell; reproductive system; shield; and unfertilized egg. Orthologous to human DDX4 (DEAD-box helicase 4).

Predicted to be involved in meiotic cell cycle and spermatid development. Predicted to be active in synaptonemal complex. Is expressed in germ line cell; male organism; and reproductive system. Human ortholog(s) of this gene implicated in spermatogenic failure 4. Orthologous to human SYCP3 (synaptonemal complex protein 3).

Predicted to enable DNA polymerase processivity factor activity. Acts upstream of or within response to activity and response to bacterium. Located in nucleus. Is expressed in several structures, including anterior neural tube; head; immature eye; nervous system; and pleuroperitoneal region. Orthologous to human PCNA (proliferating cell nuclear antigen).

Enables piRNA binding activity. Involved in anatomical structure morphogenesis; germ cell development; and piRNA processing. Located in P granule. Is expressed in several structures, including blastodisc; central nervous system; eye; reproductive system; and unfertilized egg. Orthologous to several human genes including PIWIL1 (piwi like RNA-mediated gene silencing 1).

Enables G-protein alpha-subunit binding activity. Acts upstream of or within several processes, including adherens junction maintenance; embryonic morphogenesis; and germ cell migration. Located in several cellular components, including adherens junction; cell cortex; and microvillus. Part of catenin complex. Is expressed in several structures, including axial mesoderm; blastoderm; germ ring; nervous system; and pronephros. Human ortholog(s) of this gene implicated in several diseases, including blepharocheilodontic syndrome 1; breast cancer (multiple); carcinoma (multiple); cervix uteri carcinoma in situ; and reproductive organ cancer (multiple). Orthologous to human CDH1 (cadherin 1) and CDH3 (cadherin 3).