JAK2(R683G)

JAK2(R683G)

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  • ¥4800
  • Tanda
  • 美国
  • TD-26314
  • 2025年10月22日
  • ELISA, WB, IHC
  • Mouse
  • 脊椎动物
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    • 详细信息
    • 技术资料
    • 免疫原

      A synthetic peptide from the internal region of JAK2 which includes the mutation of R683G, human origin.

    • 亚型

      IgG

    • 形态

      液体

    • 保存条件

      -20℃

    • 克隆性

      单克隆

    • 标记物

      FITC

    • 适应物种

      脊椎动物

    • 保质期

      24个月

    • 抗原来源

      蛋白

    • 目录编号

      TD-26314

    • 级别

      科研级

    • 库存

      999

    • 供应商

      武汉天德

    • 宿主

      Mouse

    • 应用范围

      ELISA, WB, IHC

    • 浓度

      0.5 mg/ml

    • 靶点

      R683G

    • 抗体英文名

      Anti JAK2(R683G) Mouse Monoclonal Antibody

    • 抗体名

      JAK2(R683G)

    • 规格

      100μl

    JAK2(R683G)

    Cat. #:  TD-26314
    Size:  100 µL
    Gene Symbol:  JAK2, JTK10, THCYT3
    Description:   Anti-JAK2(R683G) Mouse Monoclonal Antibody
    Background:    JAK2 is a non-receptor tyrosine kinase. It is a number of the Janus kinase family and has been implicated in signaling by members of the type II cytokine receptor family, the GM-CSF receptor family, the gp130 receptor family, and the single chain receptors. JAK2 orthologs have been identified in all mammals for which complete genome genome data are available. Mutations of JAK2 have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other myeloproliferative disorders.
    Immunogen:   A synthetic peptide from the internal region of JAK2 which includes the mutation of R683G, human origin.
    Applications:   ELISA, WB, IHC
    Recommended Dilutions:    ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100
    Concentration:   0.5 mg/ml
    Host Species:   Mouse
    Format:   Liquid
    Clonality:   Monoclonal
    Isotype:   IgG
    Purity:   Purified from ascites
    Preservative:  No
    Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Recognizes R683G mutant, but not wild type JAK2 of vertebrates.
    Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing
    Western blot: 
     JAK2(R683G)
    Western blot analysis of recombinant JAK2(R683G) and wild type proteins. Purified His-tagged JAK2(R683G) protein (lane2) and corresponding wild type protein (lane1) were blotted with Anti-JAK2(R683G) monoclonal antibody (Cat. #TD-26314).
    Immunofluorescence:  
    JAK2(R683G)
    Immunofluorescence of cells expressing JAK2 proteins with Anti-JAK2(R683G) antibody. HEK293T cells were transfected with pCDNA3-GFP-JAK2(R683G) plasmid, pCDNA3-GFP-JAK2 (WT) plasmid, pCDNA3-GFP-JAK2 (R683S) plasmid or pCDNA3-GFP-JAK2 (R683T) plasmid, then fixed and stained with Anti-JAK2(R683G) monoclonal antibody (Cat. #TD-26314).



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