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- 2025年08月12日
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- 规格：
20 µg/100 µg
| 规格： | 20 µg | 产品价格： | ￥1980 |
|---|---|---|---|
| 规格： | 100 µg | 产品价格： | ￥4680 |
蛋白名称：E-Cadherin蛋白, E-Cadherin protein
蛋白构建：A DNA sequence encoding the human E-Cad (P12830)(Met1-Ile707) was expressed with the Fc region of human IgG1 at the C-terminus. The purified protein was biotinylated in vitro.
表达宿主：HEK293 Cells
蛋白纯度：> 90 % as determined by SDS-PAGE
蛋白活性：0
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：Gln 23 & Asp 155
蛋白分子量：The recombinant human E-Cad consists of 791 amino acids and predicts a molecular mass of 87.1 kDa.
蛋白NP号：P12830
蛋白氨基酸序列：Met1-Ile707
蛋白标签：C-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验Tracking the Transport of E-Cadherin to and From the Plasma Membrane
, it is also a key occurrence in many diseases, including cancers of epithelial origin E-cadherin is a central component of adherens junctions (AJs), which act as structural and signaling hubs in epithelial cells that oppose EMT. The loss of E-cadherin
with purified proteins. The methods described here overcome these problems. Using a mammalian expression system, a chimeric protein comprising the extracellular domain of E-cadherin fused at its C-terminus to the Fc domain of human IgG1 (E-cadherin∶Fc
human E-cadherin-IgG Fc domain fusion protein (E-cad-Fc) has recently been shown to be extremely efficient in facilitating the culture of human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells under completely defined conditions
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