CD16a/Fc gamma RIIIA,Human

Development of Novel Major Histocompatibility Complex Class I and Class II-Deficient NOD-SCID IL2R Gamma Chain Knockout Mice for Modeling Human Xenoge

Immunodeficient mice have been used as recipients of human peripheral blood mononuclear cells (PBMC) for in vivo analyses of human xeno-graft-versus-host disease (GVHD). This xeno-GVHD model system in many ways mimics the human disease

Age-Related Alterations to Natural Killer Cell Function

Human natural killer (NK) cells represent a heterogeneous lymphoid population involved in the recognition and lysis of tumor and virally infected cells. NK cells are defined by the expression of the IgG Fc receptor CD16 (FcγRIIIA) and/or CD

Use of Activated Natural Killer Cells for Tumor Immunotherapy in Mouse and Human

of their activation, but surface expression of CD16 (FcγRIII), CD56 (in humans), NKR-P1 (in rats), or NK1.1 (in mice) and the absence of the T-cell receptor complex on the cell surface have been accepted as the markers defining these effector cells.