- 询价
- 2025年11月26日
企业认证
- 详细信息
- 文献和实验
- 技术资料
- 免疫类型：
IgG2a
- 细胞形态：
淋巴样
- 运输方式：
冻存运输
- ATCC Number：
HB-292™
- 物种来源：
大鼠
- 是否是肿瘤细胞：
0
- 库存：
大量
- 生长状态：
悬浮生长
| Designations: | MECA-89 | ||
| Depositors: | EC Butcher, DP Andrew | ||
| Isotype: | IgG2a | ||
| Biosafety Level: | 1 | ||
| Shipped: | frozen | ||
| Medium & Serum: | See Propagation | ||
| Growth Properties: | suspension | ||
| Organism: | Rattus norvegicus (B cell); Mus musculus (myeloma) deposited as rat (B cell); mouse (myeloma) | ||
| Morphology: | lymphoblast |
||
| Source: | Cell Type: hybridoma: B lymphocyte; | ||
| Cellular Products: | immunoglobulin; monoclonal antibody; against murine mucosal vascular addressin (MAdCAM-1) | ||
| Permits/Forms: | In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location. | ||
| Comments: | Animals were immunized with endothelial cells from mouse mesenteric and peripheral lymph nodes. Spleen cells were fused with Sp2/0-Ag14 myeloma cells. The antibody reacts with the second Ig domain of MAdCAM-1, and is a predominant ligand for the lymphocyte mucosal homing receptor (alpha 4, beta 7 integrin heterodimer). Unlike MECA-367, MECA-89 does not inhibit alpha 4, beta 7 dependent binding in vitro. |
||
| Propagation: | ATCC complete growth medium: RPMI 1640 medium with 4.5 g/L glucose,15 mM HEPES, 2 mM L-glutamine, 0.01 mM nonessential amino acids and 0.05 mM 2-mercaptoethanol, 90%; fetal bovine serum, 10% |
||
| Subculturing: | Medium Renewal: Every 2 to 3 days Cultures can be maintained by addition or replacement of fresh medium. Start cultures at 2 X 10 exp5 cells/ml and maintain between 1 X 10 exp5 and 1 X 10 exp6 cells/ml. |
||
| Preservation: | Culture medium, 95%; DMSO, 5% | ||
| References: | 22376: Streeter PR, et al. A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature 331: 41-46, 1988. PubMed: 3340147 22636: Berlin C, et al. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell 74: 185-195, 1993. PubMed: 7687523 22937: Briskin MJ, et al. MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1. Nature 363: 461-464, 1993. PubMed: 8502297 |
||
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验CD89 分子 CD89 常用单克隆抗体或代号： 79E6,A3;(Fca R) 主要表达细胞： My,Tsub,Bsub [M] 分子质量(kDa)和结构： gp55- 75(IgSF) 功 能： IgAFc段受体,信号转导 CD89 Summary: IgA Fc receptor, binds IgA and eliminates IgA coated targets
cgaoy121 请问PKA抑制剂H89用什么溶剂来溶解，DMSO，水，培养基还是PBS？ cgaoy121 找到了，用DMSO 鱼cynthia DMSO溶解后 用什么稀释 PBS么 cgaoy121 PBS或者培养基都可以稀释 chenlinghezzx 一般是用培养基。 萍萍-2011
中秋国庆小长假来场浪漫的旅行？不存在的，别说堵的心慌，宰的憋屈，主要是没钱。作为一枚小硕，国家助学金每月不到 600 块，别说精神需求，连满足基本生活支出都困难。作为生物狗，先不要想着发表 CNS，找到好工作，走上人生巅峰，先想办法毕业吧，下面来看看科研狗到底有多穷。学霸君先带你看看各地生命科学研究生的每月收入情况。从整体上来看，港澳台和海外地区是同等级收入最高的，这可能与当地的生活成本有关；大陆地区的华北和华东是生命科学研究生收入津贴较多的地区，如华北地区硕士平均津贴为 1241.35 元
技术资料暂无技术资料 索取技术资料
