重组人CYR61现货供应

特别提示：包括重组人CYR61在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人CYR61
英文名称：Recombinant Human Cysteine-rich Angiogenic Inducer 61
产品货号：GS4551
产品规格：5μg

分子量：Approximately 39.4kDa,a single non-glycosylated polypeptide chain containing 357 amino acids.
储存条件：冷冻（-20℃）

概述

Cysteine-rich angiogenic inducer 61(Cyr61)encoded by the Cyr61 gene is a dynamically expressed,multifunctional matricellular protein and it is also a secreted,extracellular matrix(ECM)-associated signaling protein of the CCN family.Cyr61 plays essential roles in cardiovascular development during embryogenesis and regulates inflammation,wound healing and fibrogenesis in the adult.Aberrant CCN1 expression is associated with myriad pathologies,including various cancers and diseases associated with chronic inflammation.Mature human Cyr61 shares 93%amino acid sequence identity with mouse and rat Cyr61.Cyr61 consists of four domains.There are an IGFBP domain,a VWF type C domain,a TSP type I domain,and a cysteine knot domain.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞95%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine Balb/3T3 cells is less than 3.0μg/ml,corresponding to a specific activity of>330 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in citrate buffer solution,300mMNaCl,pH 3.0.
内毒素	Less than 1 EU/μg of rHuCYR61 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	TCPAACHCPL EAPKCAPGVG LVRDGCGCCK VCAKQLNEDC SKTQPCDHTK GLECNFGASS TALKGICRAQ SEGRPCEYNS RIYQNGESFQ PNCKHQCTCI DGAVGCIPLC PQELSLPNLG CPNPRLVKVT GQCCEEWVCD EDSIKDPMED QDGLLGKELG FDASEVELTR NNELIAVGKG SSLKRLPVFG MEPRILYNPL QGQKCIVQTT SWSQCSKTCG TGISTRVTND NP

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