Caspase 8/P43/P18 单克隆抗体 66093-1-Ig
文献支持

Caspase 8/P43/P18 单克隆抗体 66093-

1-Ig
收藏
  • ￥1350 - 3000
  • Proteintech已认证
  • 66093-1-Ig
  • 2025年10月13日
  • WB, IHC, IF/ICC, IP, ELISA
  • Mouse
  • human
avatar
Proteintech中国公司
品牌商
17 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原：

      Recombinant human Caspase 8 protein

    • 亚型：

      IgG2b

    • 保存条件：

      Store at -20°C. Stable for one year after shipment.

    • 克隆性：

      Monoclonal

    • 标记物：

      Unconjugated

    • 适应物种：

      human

    • 保质期：

      详见产品包装

    • 库存：

      充足

    • 宿主：

      Mouse

    • 应用范围：

      WB, IHC, IF/ICC, IP, ELISA

    • 靶点：

      Caspase 8/P43/P18

    • 抗体英文名：

      Caspase 8/P43/P18 Monoclonal antibody

    • 抗体名：

      Caspase 8/P43/P18 Monoclonal antibody

    • 规格：

      50ul/100ul/150ul

    规格：50ul产品价格：￥1350.0
    规格：100ul产品价格：￥2200.0
    规格：150ul产品价格：￥3000.0

    经过测试的应用

    Positive WB detected inJurkat cells, HeLa cells, HEK-293 cells, HepG2 cells
    Positive IP detected inHepG2 cells
    Positive IHC detected inhuman liver cancer tissue, human liver tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
    Positive IF/ICC detected inHeLa cells
    Planning an IHC experiment? We recommend our IHCeasy CASP8 Ready-To-Use IHC Kit. CASP8 primary antibody included.
    Planning an IF experiment? We recommend our CoraLite® Plus 488 and CoraLite®594 conjugated versions of this antibody.

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:2000-1:10000
    Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
    Immunohistochemistry (IHC)IHC : 1:100-1:400
    Immunofluorescence (IF)/ICCIF/ICC : 1:400-1:1600
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    66093-1-Ig targets Caspase 8/P43/P18 in WB, IHC, IF/ICC, IP, CoIP, ELISA applications and shows reactivity with human samples.

    经测试应用 WB, IHC, IF/ICC, IP, ELISA
    文献引用应用WB, IHC, IF, IP, CoIP, ELISA
    经测试反应性 human
    文献引用反应性human, mouse, rat, pig, monkey, chicken, sheep
    免疫原

    CatNo: Ag20524

    Product name: Recombinant human Caspase 8 protein

    Source: e coli.-derived, PET28a

    Tag: 6*His

    Domain: 1-270 aa of BC028223

    Sequence: MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGTV
    宿主/亚型 Mouse / IgG2b
    抗体类别 Monoclonal
    产品类型 Antibody
    全称 caspase 8, apoptosis-related cysteine peptidase
    别名 CASP8, Caspase 8, 2B9H8, Apoptotic cysteine protease, Apoptotic protease Mch-5
    计算分子量 538 aa, 62 kDa
    观测分子量 53-57 kDa, 32-45 kDa, 18 kDa
    GenBank蛋白编号BC028223
    基因名称 Caspase 8
    Gene ID (NCBI) 841
    RRIDAB_11232214
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein A purification
    UNIPROT IDQ14790
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3 (PMID:21816816). It may control diabetic embryopathy-associated apoptosis via regulation of the Bid-stimulated mitochondrion/caspase-9 pathway (PMID:19194987). Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibody can recognize pro- and cleaved-caspase 8.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献
    SpeciesApplicationTitle
    humanWB

    Cancer Commun (Lond)

    Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies

    Authors - Lu Tang
    humanWB

    Mol Cell

    Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover.

    Authors - Dianrong Li
    • KO Validated
    humanWB

    J Adv Res

    Tetrahydrocurcumin targets TRIP13 inhibiting the interaction of TRIP13/USP7/c-FLIP to mediate c-FLIP ubiquitination in triple-negative breast cancer

    Authors - Yu-Jie Sun
    humanWB,IHC

    Acta Biomater

    TRAIL-modified, doxorubicin-embedded periodic mesoporous organosilica nanoparticles for targeted drug delivery and efficient antitumor immunotherapy.

    Authors - Xinyao Feng
    mouseWB

    J Pineal Res

    Melatonin alleviates weanling stress in mice: involvement of intestinal microbiota.

    Authors - Wenkai Ren
    humanWB,IF

    Chem Sci

    Integration of exonuclease III-powered three-dimensional DNA walker with single-molecule detection for multiple initiator caspases assay.

    Authors - Meng Liu
    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Caspase 8/P43/P18 单克隆抗体, PBS Only 66093-1-PBS
    ￥5800
    Proteintech中国公司
    2025年10月09日询价
    Caspase 8/p43/p18 Monoclonal antibody
    ￥500
    北京百奥创新科技有限公司
    2025年07月11日询价
    Caspase 6 p18 Antibody/Caspase 6 p18 Antibody/Caspase 6 p18 Antibody
    询价
    艾美捷科技有限公司
    2025年07月15日询价
    Caspase 2/p18 抗体
    ￥1050
    无锡莱弗思生物实验器材有限公司
    2025年07月12日询价
    Caspase-6 p18
    ￥1125
    攸碧艾（上海）生物技术有限公司
    2025年07月15日询价
    文献支持
    Caspase 8/P43/P18 单克隆抗体 66093-1-Ig
    ￥1350 - 3000