Recombinant Human TrkA / NTRK1 Protein (aa 194-413, His Tag)
库存:
99
供应商:
北京义翘神州科技股份有限公司
规格:
100 µg
人 TrkA蛋白|TrkA protein|TrkA(Human, N-His)(产品说明)
蛋白名称:TrkA蛋白, TrkA protein
蛋白构建:A DNA sequence encoding the amino acid sequence (Pro 194-Glu 413) of human NTRK1 (NP_002520.2), corresponding to the Ig-like C2-type 1 & 2 domains, was expressed and purified, with a N-terminal polyhistidine tag.
表达宿主:HEK293 Cells
蛋白纯度:> 95 % as determined by SDS-PAGE
蛋白活性:Measured by its ability to inhibit NGF-induced proliferation of TF1 human erythroleukemic cells. The ED50 for this effect is typically 0.5-4 μg/ml in the presence of 10 ng/mL of human NGF.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:His
蛋白分子量:The recombinant human NTRK1 Ig-like C2-type 1 & 2 domains (aa 194-413) consists of 239 amino acids and has a predicted molecular mass of 26 kDa. As a result of glycosylation, it migrates as an approximately 45-50 kDa band in SDS-PAGE under reducing conditions.
蛋白NP号:NP_002520.2
蛋白氨基酸序列:Pro194-Glu413
蛋白标签:N-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
1, Song, QQ; et al. Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway. Acta pharmacologica Sinica, Pubmed: 36482085