Sample:
Lane 1: Mouse Liver tissue lysates
Lane 2: Rat Lung tissue lysates
Primary: Anti-SLC38A2 (bs-12125R) at 1/200 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56 kDa
Observed band size: 60 kDa
- ￥1180 - 2800
- Bioss
- bs-12125R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-12125R |
| 英文名称 | SLC38A2 Rabbit pAb |
| 中文名称 | 氨基酸转运蛋白2抗体 |
| 英文别名 | Amino acid transporter 2; Amino acid transporter A2; ATA2; SNAT2; KIAA1382; PRO1068; Protein 40-9-1; S38A2_HUMAN; SAT2; Slc38a2; Sodium-coupled neutral amino acid transporter 2; Solute carrier family 38 member 2; System A amino acid transporter; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human, Dog, Pig, Cow, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SLC38A2/SNAT2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 56 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Cell membrane. Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes. Enriched in the somatodendritic compartment of neurons, it is also detected at the axonal shaft but excluded from the nerve terminal. |
| 组织特异性 | Ubiquitously expressed. Widely expressed in the central nervous system with higher concentrations in caudal regions. Expressed by glutamatergic and GABAergic neurons together with astrocytes and other non-neuronal cells in the cerebral cortex (at protein level). |
| 翻译后修饰 | Polyubiquitination by NEDD4L regulates the degradation and the activity of SLC38A2. |
| 相似性 | Belongs to the amino acid/polyamine transporter 2 family. |
| 功能 | Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. SNAT2, also designated ATA2, PRO1068 and SAT2 is encoded by the human gene SLC38A2. The functional role of SNAT2 in the nervous system is unclear. Protein expression is notably enriched in the spinal cord and brain stem nuclei of the auditory system. System A transport proteins are also present in placental tissue. These SNAT proteins may play a significant role in fetal development and inhibition of the transport system has been associated with fetal growth retardation. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 5.1 }}] {Xiaoyue Ma. et al. Prolactin Modulates the Proliferation and Secretion of Goat Mammary Epithelial Cells via Regulating Sodium-Coupled Neutral Amino Acid Transporter 1 and 2. CELLS-BASEL. 2024 Jan;13(17):1461} {WB} {Goat}
[IF={{ 5.076 }}] {Hu C et al. Placentae for Low Birth Weight Piglets Are Vulnerable to Oxidative Stress, Mitochondrial Dysfunction, and Impaired Angiogenesis. Oxid Med Cell Longev. 2020 May 25;2020:8715412.} {WB} {Pig}
[IF={{ 3.6 }}] {Mingzhi Xia. et al. miR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2. CANCER BIOL THER. 2024 Feb 23} {WB} {Mouse,Human}
[IF={{ 3.5 }}] {Jiang Tingting. et al. SNAT2-mediated regulation of estrogen and progesterone in the proliferation of goat mammary epithelial cells. AMINO ACIDS. 2024 Dec;56(1):1-12} {WB} {Goat}
[IF={{ 3.478 }}] {Jan Remsik. et al. Characterization, isolation and in vitro culture of leptomeningeal fibroblasts. J Neuroimmunol. 2021 Sep;:577727} {IF} {mouse }
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SLC38A2 Rabbit pAb(bs-12125R)-50ul/100ul/200ul
￥1180 - 2800
