- ￥1600 - 2650
- MultiSciences
- 31.25 pg/mL - 2000 pg/mL
- 浙江杭州
- EK301B-96
- 2025年12月17日
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- 文献和实验
- 技术资料
- 库存：
99
- 供应商：
联科生物
- 检测范围：
31.25 pg/mL - 2000 pg/mL
- 检测方法：
双抗夹心法
- 应用：
ELISA
- 适应物种：
Rat
- 标记物：
NoData
- 样本：
血清、血浆、细胞上清
- 规格：
96T/48T
| 规格： | 96T | 产品价格： | ￥2650.0 |
|---|---|---|---|
| 规格： | 48T | 产品价格： | ￥1600.0 |
本试剂盒采用双抗体夹心酶联免疫吸附法定量检测大鼠IL-1β。大鼠IL-1β试剂盒仅供科学研究，不用于临床诊断。白细胞介素 1 (IL-1)是 17 kDa 的胞外多肽，分为 IL-1α 和 IL-1β 两种蛋白。 IL-1β 是活化的巨噬细胞分泌的蛋白前体， 通过 caspase 1 (CASP1/ICE)水解产生的活化形式。 该细胞因子是炎症反应的重要介导者，参与许多细胞活性，包括细胞增殖、分化和凋亡。 IL-1 是一类重要的蛋白家族，它们由生物活化的单核细胞所衍生， 参与炎症反应和免疫应答。IL-1β 表达升高会产生各种不同的自身炎症综合征， 最显著的是单基因条件称为 CAPS，是由于触发 IL-1β 加工的炎性体受体 NLRP3 发生突变而引起的。
分析类型：夹心ELISA
样本类型:血清、血浆、细胞上清
产品型式:96孔板，可拆
贮存方法：试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件：4℃
样本体积：20μl
灵敏度：1.42pg/ml
标准曲线范围：31.25-2000pg/ml
回收率范围：84%-110%
平均回收率：1.02
板间变异系数:5.0%-5.1%
板内变异系数:5.5%-6.7%
【说明书】 大鼠白介素1beta试剂盒Rat IL-1beta ELISA Kit说明书
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- IF = 4.451 Inhibition of Toll-Like Receptor 4 Signaling Pathway Accelerates the Repair of Avascular Necrosis of Femoral Epiphysis through Regulating Macrophage Polarization in Perthes Disease. Tissue Engineering and Regenerative Medicine (2023)
- IF = 4.414 1H NMR Spectroscopy-Based Metabolomics Approach to Study the Anti-Stroke Activity of G-3702, a Novel Better Alternative to DL-3-n-Butylphthalide. NEUROCHEMICAL RESEARCH (2022)
- IF = 4.412 The Effect of Protein-Rich Extract from Bombyx Batryticatus against Glutamate-Damaged PC12 Cells Via Regulating γ-Aminobutyric Acid Signaling Pathway. MOLECULES (2020)
- IF = 4.374 Pirfenidone inhibits epithelial-mesenchymal transition and pulmonary fibrosis in the rat silicosis model. TOXICOLOGY LETTERS (2018)
- IF = 4.36 Huang-Lian-Jie-Du decoction attenuates cognitive dysfunction of rats with type 2 diabetes by regulating autophagy and NLRP3 inflammasome activation. JOURNAL OF ETHNOPHARMACOLOGY (2022)
- IF = 4.36 Effect of Shixiao San on inflammatory factors and pain in rats with endometriosis. JOURNAL OF ETHNOPHARMACOLOGY (2022)
- IF = 4.36 Metabolomics combined with network pharmacology to study the mechanism of Shentong Zhuyu decoction in the treatment of rheumatoid arthritis. JOURNAL OF ETHNOPHARMACOLOGY (2021)
- IF = 4.36 Berberis kansuensis extract alleviates type 2 diabetes in rats by regulating gut microbiota composition. JOURNAL OF ETHNOPHARMACOLOGY (2021)
- IF = 4.225 Tetramethylpyrazine Ameliorates Lipopolysaccharide-Induced Sepsis in Rats via Protecting Blood–Brain Barrier, Impairing Inflammation and Nitrous Oxide Systems. Frontiers in Pharmacology (2020)
- IF = 4.225 The Anti-Depressive Effects of Hesperidin and the Relative Mechanisms Based on the NLRP3 Inflammatory Signaling Pathway. Frontiers in Pharmacology (2020)
- IF = 4.225 1H NMR-Based Metabolomics Coupled With Molecular Docking Reveal the Anti-Diabetic Effects and Potential Active Components of Berberis vernae on Type 2 Diabetic Rats. Frontiers in Pharmacology (2020)
- IF = 4.219 Salidroside alleviates diabetic neuropathic pain through regulation of the AMPK-NLRP3 inflammasome axis. TOXICOLOGY AND APPLIED PHARMACOLOGY (2021)
- IF = 4.219 miR-181b-5p inhibits endothelial-mesenchymal transition in monocrotaline-induced pulmonary arterial hypertension by targeting endocan and TGFBR1. TOXICOLOGY AND APPLIED PHARMACOLOGY (2019)
- IF = 4.196 Pharmacological Investigation of the Anti-Inflammation and Anti-Oxidation Activities of Diallyl Disulfide in a Rat Emphysema Model Induced by Cigarette Smoke Extract. Nutrients (2018)
- IF = 4.174 Down-regulation of long non-coding RNA XIST aggravates sepsis-induced lung injury by regulating miR-16-5p. Human Cell (2021)
- IF = 4.162 Orally Deliverable Dual-Targeted Pellets for the Synergistic Treatment of Ulcerative Colitis. Drug Design Development and Therapy (2021)
- IF = 4.162 Qing-Luo-Yin Alleviated Monocytes/Macrophages-Mediated Inflammation in Rats with Adjuvant-Induced Arthritis by Disrupting Their Interaction with (Pre)-Adipocytes Through PPAR-γ Signaling. Drug Design Development and Therapy (2021)
- IF = 4.162 Magnesium Isoglycyrrhizinate Alleviates Arsenic Trioxide-Induced Cardiotoxicity: Contribution of Nrf2 and TLR4/NF-κB Signaling Pathway. Drug Design Development and Therapy (2021)
- IF = 4.162 Baicalin Rescues Cognitive Dysfunction, Mitigates Neurodegeneration, and Exerts Anti-Epileptic Effects Through Activating TLR4/MYD88/Caspase-3 Pathway in Rats. Drug Design Development and Therapy (2021)
- IF = 4.146 Mechanism of Incisional Pain: Novel Finding on Long Noncoding RNA XIST/miR-340-5p/RAB1A Axis:. ASN Neuro (2021)
- IF = 4.133 Glycogen synthase kinase-3β inhibition alleviates activation of the NLRP3 inflammasome in myocardial infarction. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2020)
- IF = 4.119 The therapeutic effects of Prunella vulgaris against fluoride-induced oxidative damage by using the metabolomics method. ENVIRONMENTAL TOXICOLOGY (2021)
- IF = 4.092 Protective Effects of 18β-Glycyrrhetinic Acid on Neonatal Rats with Hyperoxia Exposure. INFLAMMATION (2022)
- IF = 4.092 MicroRNA-181b Inhibits Inflammatory Response and Reduces Myocardial Injury in Sepsis by Downregulating HMGB1. INFLAMMATION (2021)
- IF = 4.079 Paeonol attenuates ligation-induced periodontitis in rats by inhibiting osteoclastogenesis via regulating Nrf2/NF-κB/NFATc1 signaling pathway. BIOCHIMIE (2018)
- IF = 4.061 Therapeutic Potential of Liraglutide for Diabetes–Periodontitis Comorbidity: Killing Two Birds with One Stone. Journal of Diabetes Research (2022)
- IF = 4.061 San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.. Journal of Diabetes Research (2022)
- IF = 4.044 Gastric smooth muscle cells manifest an abnormal phenotype in Parkinson’s disease rats with gastric dysmotility. CELL AND TISSUE RESEARCH (2020)
- IF = 4.003 Long Non-coding RNAMALAT1 Knockdown Alleviates Cerebral Ischemia/Reperfusion Injury of Rats Through Regulating the miR-375/PDE4D Axis. Frontiers in Neurology (2021)
- IF = 3.943 Nervilifordin F alleviates intestinal ischemia/reperfusion-induced acute lung injury via inhibiting inflammasome and mTOR pathway. INTERNATIONAL IMMUNOPHARMACOLOGY (2020)
- IF = 3.935 Metabolomics and pharmacodynamic analysis reveal the therapeutic role of Prunella vulgaris oil on intrauterine adhesion rats. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2021)
- IF = 3.935 Systematic investigation on the anti-rheumatoid arthritis material basis and mechanism of Juan Bi Tang. Part 1: Integrating metabolic profiles and network pharmacology. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2021)
- IF = 3.932 Cangxitongbi capsules protect the articular cartilage in the rat knee through the long non-coding RNA HOTAIR/p38MAPK pathway. Annals of Translational Medicine (2022)
- IF = 3.926 Protective effects of methylprednisolone–cyclophosphamide treatment on bleomycin-induced pulmonary fibrosis. CYTOKINE (2023)
- IF = 3.915 Resveratrol alleviates early brain injury following subarachnoid hemorrhage: possible involvement of the AMPK/SIRT1/autophagy signaling pathway. BIOLOGICAL CHEMISTRY (2018)
- IF = 3.9 Necrostatin-1 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain by Inhibiting the RIP1/RIP3 Pathway. Frontiers in Cellular Neuroscience (2019)
- IF = 3.831 Integrated Serum and Fecal Metabolomics Study of Collagen-Induced Arthritis Rats and the Therapeutic Effects of the Zushima Tablet. Frontiers in Pharmacology (2018)
- IF = 3.758 Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis. MEDIATORS OF INFLAMMATION (2020)
- IF = 3.752 Leonurine inhibits cardiomyocyte pyroptosis to attenuate cardiac fibrosis via the TGF-β/Smad2 signalling pathway. PLoS One (2022)
- IF = 3.743 Modification effects of SanWei GanJiang Powder on liver and intestinal damage through reversing bile acid homeostasis. BIOMEDICINE & PHARMACOTHERAPY (2019)
- IF = 3.727 Non-Invasive Local Acoustic Therapy Ameliorates Diabetic Heart Fibrosis by Suppressing ACE-Mediated Oxidative Stress and Inflammation in Cardiac Fibroblasts. CARDIOVASCULAR DRUGS AND THERAPY (2022)
- IF = 3.707 MiR-128-3p Alleviates Spinal Cord Ischemia/Reperfusion Injury Associated Neuroinflammation and Cellular Apoptosis via SP1 Suppression in Rat. Frontiers in Neuroscience (2020)
- IF = 3.706 Dihydromyricetin Inhibits Inflammation of Fibroblast-like Synoviocytes through Regulation of NF-κB Signaling in Collagen-Induced Arthritis Rats. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2018)
- IF = 3.693 Protective effect of active components of Eucommia ulmoides leaves on gastric ulcers in rats: Involvement of the PI3K/Akt/NF-κB pathway. JOURNAL OF FOOD SCIENCE (2022)
- IF = 3.69 Polysaccharides and glycosides from Aralia echinocaulis protect rats from arthritis by modulating the gut microbiota composition. JOURNAL OF ETHNOPHARMACOLOGY (2020)
- IF = 3.69 Ethyl acetate extract of Tibetan medicine Rhamnella gilgitica ameliorated type II collagen-induced arthritis in rats via regulating JAK-STAT signaling pathway. JOURNAL OF ETHNOPHARMACOLOGY (2020)
- IF = 3.659 Alkaloids from piper longum protect dopaminergic neurons against inflammation-mediated damage induced by intranigral injection of lipopolysaccharide. BMC Complementary and Alternative Medicine (2016)
- IF = 3.61 Decreased brain noradrenaline in minimal hepatic encephalopathy is associated with cognitive impairment in rats. BRAIN RESEARCH (2022)
- IF = 3.584 Paeoniflorin attenuates early brain injury through reducing oxidative stress and neuronal apoptosis after subarachnoid hemorrhage in rats. METABOLIC BRAIN DISEASE (2020)
- IF = 3.575 Chronic microglial inflammation promotes neuronal lactate supply but impairs its utilization in primary rat astrocyte-neuron co-cultures. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022)
- IF = 3.575 Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)
- IF = 3.575 Melatonin alleviates cigarette smoke-induced endothelial cell pyroptosis through inhibiting ROS/NLRP3 axis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
- IF = 3.575 Fibroblast growth factor 21 attenuates hypoxia-induced pulmonary hypertension by upregulating PPARγ expression and suppressing inflammatory cytokine levels. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
- IF = 3.558 Transcutaneous Auricular Vagus Nerve Stimulation Promotes White Matter Repair and Improves Dysphagia Symptoms in Cerebral Ischemia Model Rats. Frontiers in Behavioral Neuroscience (2022)
- IF = 3.55 S‐Allylmercaptocysteine Attenuates Cisplatin‐Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation. Nutrients (2017)
- IF = 3.545 NPY Receptor 2 Mediates NPY Antidepressant Effect in the mPFC of LPS Rat by Suppressing NLRP3 Signaling Pathway. MEDIATORS OF INFLAMMATION (2019)
- IF = 3.516 Glutathione Supplementation Attenuates Oxidative Stress and Improves Vascular Hyporesponsiveness in Experimental Obstructive Jaundice. Oxidative Medicine and Cellular Longevity (2015)
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大鼠白介素1beta试剂盒Rat IL-1beta ELISA Kit Rat IL-1β
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