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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃ to -80℃
- 保质期:
12个月
- 英文名:
Recombinant Human c-MET / HGFR Protein (His Tag)
- 库存:
99
- 供应商:
北京义翘神州科技股份有限公司
- 规格:
1.00 mg/50.00 µg/100.00 µg
| 规格: | 1.00 mg | 产品价格: | ¥16560.0 |
|---|---|---|---|
| 规格: | 50.00 µg | 产品价格: | ¥2310.0 |
| 规格: | 100.00 µg | 产品价格: | ¥3220.0 |
重组人 c-MET / HGFR 蛋白 (His标签)(产品说明)
蛋白名称:Human c-MET / HGFR Protein (His Tag)
蛋白构建:A DNA sequence encoding the extracellular domain of human c-Met (NP_000236.2) (Met1-Thr932) was fused with a polyhistidine tag at the C-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 90 % as determined by SDS-PAGE
蛋白活性:Immobilized Cynomolgus HGF(Cat:90286-CNAH) at 2 μg/mL (100 μL/well) can bind Human c-MET His(Cat:10692-H08H), the EC50 of Human c-MET His(Cat:10692-H08H) is 20-120ng/mL.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Glu 25
蛋白分子量:The mature form of recombinant human c-Met is a disulfide-linked heterodimer composed of proteolytically cleaved α and β subunits. Each α and β subunit together consists of 919 amino acids and has a predicted molecular mass of 103 (α=33 +β=70) kDa. As a result of glycosylation, rh c-MET heterodimer thus migrates with apparent molecular mass of approximately 45 kDa and 85 kDa respectively in SDS-PAGE under reducing conditions.
蛋白NP号:NP_000236.2
蛋白氨基酸序列:Met1-Thr932
蛋白标签:C-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
蛋白名称:Human c-MET / HGFR Protein (His Tag)
蛋白构建:A DNA sequence encoding the extracellular domain of human c-Met (NP_000236.2) (Met1-Thr932) was fused with a polyhistidine tag at the C-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 90 % as determined by SDS-PAGE
蛋白活性:Immobilized Cynomolgus HGF(Cat:90286-CNAH) at 2 μg/mL (100 μL/well) can bind Human c-MET His(Cat:10692-H08H), the EC50 of Human c-MET His(Cat:10692-H08H) is 20-120ng/mL.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Glu 25
蛋白分子量:The mature form of recombinant human c-Met is a disulfide-linked heterodimer composed of proteolytically cleaved α and β subunits. Each α and β subunit together consists of 919 amino acids and has a predicted molecular mass of 103 (α=33 +β=70) kDa. As a result of glycosylation, rh c-MET heterodimer thus migrates with apparent molecular mass of approximately 45 kDa and 85 kDa respectively in SDS-PAGE under reducing conditions.
蛋白NP号:NP_000236.2
蛋白氨基酸序列:Met1-Thr932
蛋白标签:C-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验该产品被引用文献
1, Li K, et al. Anti-MET immunoPET for non-small cell lung cancer using fully human antibody fragments.Molecular cancer therapeutics, PubMed ID: 25143449
2, Wu X, et al. Detection of colonic neoplasia in vivo using near-infrared-labeled peptide targeting cMet.Scientific reports, PubMed ID: 31784601
3, Yuan X, et al. Dual-function chimeric antigen receptor T cells targeting c-Met and PD-1 exhibit potent anti-tumor efficacy in solid tumors.Investigational new drugs, PubMed ID: 32772342
4, Lim RK, et al. Discovery of novel cMET-targeting antibody Fab drug conjugates as potential treatment for solid tumors with highly expressed cMET.Expert opinion on biological therapy, PubMed ID: 38078403
5, Gera N, et al. MYTX-011: a pH-dependent anti-cMET antibody-drug conjugate designed for enhanced payload delivery to cMET expressing tumor cells.Molecular cancer therapeutics, PubMed ID: 38684230
2, Wu X, et al. Detection of colonic neoplasia in vivo using near-infrared-labeled peptide targeting cMet.Scientific reports, PubMed ID: 31784601
3, Yuan X, et al. Dual-function chimeric antigen receptor T cells targeting c-Met and PD-1 exhibit potent anti-tumor efficacy in solid tumors.Investigational new drugs, PubMed ID: 32772342
4, Lim RK, et al. Discovery of novel cMET-targeting antibody Fab drug conjugates as potential treatment for solid tumors with highly expressed cMET.Expert opinion on biological therapy, PubMed ID: 38078403
5, Gera N, et al. MYTX-011: a pH-dependent anti-cMET antibody-drug conjugate designed for enhanced payload delivery to cMET expressing tumor cells.Molecular cancer therapeutics, PubMed ID: 38684230
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c-MET/HGFR重组蛋白|Recombinant Human c-MET / HGFR Protein (His Tag)
¥2310 - 16560





