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- 2025年08月12日
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- 规格：
100 µg
蛋白名称：Calcitonin receptor蛋白, Calcitonin receptor protein
蛋白构建：A DNA sequence encoding the human CALCR (NP_001158209.1) (Ala25-Val154) was expressed with the Fc region of human IgG1 at the N-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 90 % as determined by SDS-PAGE.
蛋白活性：0
蛋白内毒素：< 1.0 EU per μg protein as determined by the LAL method.
预测N端：Glu
蛋白分子量：The recombinant human CALCR consists 390 amino acids and predicts a molecular mass of 43.9 kDa.
蛋白NP号：NP_001158209.1
蛋白氨基酸序列：Ala25-Val154
蛋白标签：N-human IgG1-Fc
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验为对兔疫球蛋白Fc部分c末端的受体。对具有该受体的细胞，通过抗体与抗原结合时，细胞将发挥如下的特有机能：（1）原噬菌体对IgG，占多形核白细胞大部分的嗜中性细胞对IgG、IgA具有Fc受体，通常通过与抗原结合的抗体以及有时与游离的抗体（嗜细胞性抗体）结合来捕捉抗原，并经吞噬作用将之围吞。（2）B细胞的大部分（80%以上）具有对IgG的Fc受体，这些都不进行产生抗体的细胞分化，可通过与抗原抗体复合体的结合而被活化，释放产生抗体的细胞限制因子。（3）T细胞约有10%具有Fc受体，主要
Characterization of CGRP Receptor Binding
, P.M. 2000. Amylin receptor phenotypes derived from human calcitonin receptor/RAMP coexpression exhibit pharmacological differences dependent on receptor isoform and host cell environment. J. Pharmacol. Exp. Ther. 294:61‐72
Analysis of Function of Receptor-G-Protein and Receptor-RGS Fusion Proteins
in detail. The process of fusing the two components, the receptor and the G-protein α-subunit, result in a construct that acts as an agonist stimulated GTPase enzyme whose expression level can be accurately determined by radioligand binding. The effects of different
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