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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
2-8°C
- 保质期：
1年
- 英文名：
Toyocamycin
- 库存：
30⁺瓶
- 供应商：
上海睿安生物19121878899
- CAS号：
606-58-6
- 规格：
50mg/瓶
Tocris货号5270-10mg现货Toyocamycin上海睿安生物19121878899
安迪Bio-Techne(R&D Systems-Tocris)官方正式授权代理商
Tocris货号5270-50mg现货Toyocamycin上海睿安生物19121878899
Chemical Name:4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
Purity:≥98%
Biological Activity
Toyocamycin is an adenosine analog; antifungal antibiotic. Inhibits RNA self-cleavage in HEK79 cells and PI 3-kinase activity in A431 epidermoid carcinoma cell membrane fractions. Also inhibits thapsigargin-induced XBP1-luciferase activation and induces apoptosis in multiple myeloma cell lines.Technical Data
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
- Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing.
Ri et al.
Blood.Cancer.J., 2012;2:e79 - Inhibition of phosphatidylinositol kinase by toyocamycin.
Nishioka et al.
J.Antibiot. (Tokyo)., 1990;43:1586 - Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries.
Yen et al.
RNA, 2006;12:797
Citation for Toyocamycin
The citations listed below are publications that use Tocris products. Selected citations for Toyocamycin include:
1 Citation: Showing 1 - 1
- IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.
Authors: Tanabe Et al.
Oncotarget 2018;9:14428
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文献和实验Tocris货号5270-10mg现货Toyocamycin上海睿安生物19121878899
安迪Bio-Techne(R&D Systems-Tocris)官方正式授权代理商
Tocris货号5270-50mg现货Toyocamycin上海睿安生物19121878899
Chemical Name:4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
Purity:≥98%
Biological Activity
Toyocamycin is an adenosine analog; antifungal antibiotic. Inhibits RNA self-cleavage in HEK79 cells and PI 3-kinase activity in A431 epidermoid carcinoma cell membrane fractions. Also inhibits thapsigargin-induced XBP1-luciferase activation and induces apoptosis in multiple myeloma cell lines.Technical Data
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
- Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing.
Ri et al.
Blood.Cancer.J., 2012;2:e79 - Inhibition of phosphatidylinositol kinase by toyocamycin.
Nishioka et al.
J.Antibiot. (Tokyo)., 1990;43:1586 - Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries.
Yen et al.
RNA, 2006;12:797
Citation for Toyocamycin
The citations listed below are publications that use Tocris products. Selected citations for Toyocamycin include:
1 Citation: Showing 1 - 1
- IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.
Authors: Tanabe Et al.
Oncotarget 2018;9:14428
学术论文投稿流程，建议收藏！ 在线提交稿件和同行评审系统已成为现代学术研究和论文发表过程中不可或缺的内容。本文带您一起来了解将待发表稿件提交给目标期刊的实用建议和注意事项。 1、稿件在线提交和同行评审系统 目前，大多数学术期刊一般都采用在线投稿系统来促进作者、编辑和审稿人之间的快速和无缝沟通。常见的在线投稿系统包括 Editorial Manager、Manuscript Central、Open Journal Systems 等等，它们的在线投稿过程有相似之处，不过可能在检查清单或所需
, Pan troglodytes, Gorilla gorilla, and Pongo pygmaeus). J Comp Psychol 118:232–241[3]Fox, B. A., Sanders, K. L., Rommereim, L. M., Guevara, R. B., & Bzik, D. J. (2016). Secretion of rhoptry and dense granule effector proteins by nonreplicating
= 4x = 52 n = 2x = 26 hexaploid植物其haploid为triploid 普通小麦2n = 6x = 42 n = 3x = 21 octoploid植物其haploid为tetraploid 草莓 2n = 8x = 56 n = 4x = 28 单倍体植物与它们的二倍体相比较，有三个明显的特点： · 体细胞染色体数减半； · 生长发育弱，体形小、各器官明显减小；
