CD44 (CD44) (AA 21-145) 抗体

CD44 (CD44) (AA 21-145) 抗体抗原
CD44 (CD44)
别名 AU023126, AW121933, AW146109, HERMES, Ly-24, Pgp-1, CD44A, METAA, RHAMM, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1
抗原表位
其他选择 AA 21-145
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (5C10)
标记
其他选择 非结合性
CD44 (CD44) (AA 21-145) 抗体应用范围
其他选择 酵素免疫分析法（EIA）, Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), 免疫组织化学石蜡技术（IHC-P）
Pubmed 2个引用可参考
规格 0.1 mL
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb263995
产品细节
免疫原 Recombinant Human CD44 (aa 21-145) purified from E. coli
CD44 (CD44) (AA 21-145) 抗体克隆位点 5C10
亚型 IgG2b
特异性 This antibody detects Human CD44 / HUTCH-I.
交叉反应 （详细） Species reactivity (tested):Human.
产品特性 Synonyms: CDw44, PGP-I, ECMR-III, Hermes antigen, Epican, LHR, MDU2, MDU3, MIC4, Phagocyticglycoprotein I, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesionreceptor, Hyaluronate receptor, Heparan sulfate proteoglycan
纯化方法 Protein-G affinity chromatography
目标详细情况
别名 CD44
背景 CD44 is a broadly distributed transmembrane glycoprotein that plays a critical role in a variety of cellular behaviors, including adhesion, migration, invasion, and survival. CD44 mediates cell-cell and cell-matrix interactions in a large part through its affinity for hyaluronan (HA), a glycosaminoglycan constituent of extracellular matrices, but also potentially through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Variants of CD44 are expressed in tissues during development, including embryonic epithelia. Known functions of CD44 are cellular adhesion (aggregation and migration), hyaluronate degradation, lymphocyte activation, lymph node homing, myelopoiesis and lymphopoiesis, angiogenesis, and release of cytokines. The functions of CD44 are principally dependant on cellular adhesion in one setting or another.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1
基因ID 960
UniProt P16070
研究领域 Stem Cells, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells, Cancer, Cell Cycle
使用细节
应用备注 ELISA. Western blot: 1/1,000-1/2,000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理
状态 Liquid
浓度 1.0 mg/mL
缓冲液 PBS, pH 7.4, containing 0.09 % Sodium Aziden as preservative.
储存液 Sodium azide
CD44 (CD44) (AA 21-145) 抗体注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
有效期 12 months