PCR Analysis of CD44 Variants in Tumors
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The CD44 molecule is a transmembrane glycoprotein, it is an acidic, sul fated protein that contains multiple phosphoserine residues and several intrachain disulfide bonds. It is essentially composed of a 37-kDa protein core highly glycosylated by N - and O -linked sugars to form an 85–90-kDa product and is sometimes additionally linked to chondroitin sulfate side chains to produce a 180–220 kDa form on sodium dodecyl sulfate (SDS) gels (1 ,2 ).
