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- 克隆性：
单克隆
- 抗体英文名：
Anti-MMP-11(matrix m
- 抗体名：
北京博奥森生物技术有限公司
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1 proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. MMP11, also known as stromelysin 3, is overexpressed in the stromal cells of invasive breast carcinomas but not in the stromal cells surrounding benign breast fibroadenomas. MMP11 is secreted in its proenzyme from and the zymogen has a mass of 64 kDa. The enzyme is rapidly activated to a 58 kDa form, a 45-47 kDa size, then to a 28 kDa final active form. MMP11 is not constitutively produced by most cell types. It has been found in lung fibroblasts and gingival fibroblasts when stimulated with EGF, as well as breast tumor and osteocarcinoma cell lines.
mol wt:55kDa
Other Aliases:
matrix metalloproteinase 11; Stromelysin-3; SL-3; Short=ST3; Matrix metalloproteinase-11
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文献和实验【原创】转载Western Blot 内参选择攻略（美季生物技术有限公司）http://www.majorbio.cn/NewsInfo.asp?id=289
Western Blot 内参选择 要检测一个基因的表达产物是否正确，或者比较表达产物量的相对变化，首选方法是Western Blot。因为Western Blot操作相对简单方便，既可以定性分析表达产物，同时还可以指示目的蛋白量的相对变化。虽然，顺利的时候Western Blot做起来很简单，可不顺的时候也很令人心烦――做不出结果啦、假阳性啦、结果出现多条带啦、到底是一抗有问题还是二抗有问题啦……毕竟，作为一种有活性的生物大分子，抗体
工作效率，为实验制定严格时间进度而不会受其它因素影响，科研人员将会有更多的时间和精力从事创新性的工作。海基生物可为客户提供以下分子生物学服务：大规模的核酸提取及纯化，PCR克隆及亚克隆，RT-PCR, Real-time PCR, 基因突变， 载体 构建，基因敲除, 质粒制备，SNP检测及数据分析等。凭借其丰富的生物技术服务经验，海基生物的分子生物学团队完全可以为客户解决任何技术难题。 2.上海锐赛生物技术有限公司 上海锐赛是由一群海内外从事科学技术研究和生物技术
jerome520 我现在急做一批样本的microRNA检测（只检测一个指标），用茎环法，想要送去公司做。康成生物高手们有听说过吗？还有其他代做的公司推荐吗？谢谢！！！ zaoyii 我知道广州伯信生物技术有限公司可以做，技术上也比较成熟，这是网站http://www.biosensechina.com/，你可以去看看或者打电话去问问：020-28069086 jerome520
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