Cadherin-5 / CDH5 / VE-Cad / C

Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. They play important roles in cell adhesion, ensuring that cells within tissues are bound together. They are dependent on calcium (Ca2+) ions to function. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of an HAV cell adhesion recognition sequence specific to type I cadherins. It has been observed that cells containing a specific cadherin subtype tend to cluster together to the exclusion of other types, both in cell culture and during development. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, is single-pass type I membrane protein. It is expressed in endothelial tissues and brain and is involved in loss of heterozygosity events in breast and prostate cancer. CDH5 is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, CDH5 may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
Cadherin-5 / CDH5 / VE-Cad / CD144抗体相关产品如下：xy-10126R LATT细胞活化连接蛋白抗体
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xy-2661R MD1MD-1蛋白抗体
xy-2662R MD-2MD-2蛋白抗体
xy-1311R LYVE-1淋巴管内皮透明质酸受体抗体
xy-0897R liver FABP肝脏型脂肪酸结合蛋白抗体
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xy-7687R LAP3亮氨酸氨基肽酶3抗体
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xy-2904R LATS1肿瘤抑制基因LATS1抗体
xy-3247R Phospho-LIMK1(Thr508) + LIMK2(Thr505)磷酸化单丝氨酸蛋白激酶1/2抗体
xy-3246R Phospho-LATS1 (Ser909)磷酸化肿瘤抑制基因LATS1抗体
xy-3248R phospho-LKB1(Ser334)磷酸化丝氨酸/苏氨酸蛋白激酶抗体
xy-3249R phospho-LKB1(Ser428)磷酸化丝氨酸/苏氨酸蛋白激酶抗体
xy-3250R Phospho-LKB1(Thr189)磷酸化丝氨酸/苏氨酸蛋白激酶抗体
xy-0456R GNRH黄体激素释放激素类似物抗体
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xy-3255R Phospho-Lck (Tyr505)磷酸化淋巴细胞特异性蛋白酪氨酸激酶抗体
xy-2906R Lyn膜相关蛋白酪氨酸激酶Lyn抗体
xy-3256R Phospho-Lyn (Tyr507)磷酸化膜相关蛋白酪氨酸激酶Lyn抗体
xy-3257R Phospho-Lyn (Tyr397)磷酸化膜相关蛋白酪氨酸激酶Lyn抗体
xy-1974R LRRC4脑瘤相关基因抗体
xy-11091R LSAMP大脑边缘系统相关膜蛋白抗体
xy-11087R LRFN2神经突触粘附样分子1抗体
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xy-11056R Laminin alpha 4层粘蛋白α4抗体(Lamininα4)
xy-11055R Laminin alpha 4层粘蛋白α4抗体(Lamininα4)
xy-11286R lipocalin 1脂质运载蛋白1抗体
xy-11287R Lymphotactin淋巴细胞趋化因子抗体
xy-11590R LRP5L低密度脂蛋白受体5样蛋白抗体
xy-11571R LRRTM3富含亮氨酸重复跨膜神经元蛋白3抗体
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xy-0961M Leptin receptor瘦素受体抗体
xy-11057R Elastin项韧带弹性蛋白抗体
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