VE-Cadherin / CD144 / CDH5抗体

VE-Cadherin / CD144 / CDH5抗体产品信息免疫原 : Recombinant Mouse VE-Cadherin / CD144 / CDH5 protein (Catalog#50192-M08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG

缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Mouse VE-Cadherin / CD144 / CDH5 (rM VE-Cadherin / CD144 / CDH5; Catalog#50192-M08H; NP_033998.2; Met 1-Ala 592). VE-Cadherin / CD144 / CDH5 specific IgG was purified by Mouse VE-Cadherin / CD144 / CDH5 affinity chromatography.
VE-Cadherin / CD144 / CDH5抗体 Background
Cadherins (Calcium dependentadhesion molecules) are a class of transmembrane proteins. They play important roles incell adhesion, ensuring that cells within tissues are bound together. They are dependent oncalcium (Ca2+)ionsto function. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of an HAV cell adhesion recognition sequence specific to type I cadherins. It has been observed that cells containing a specific cadherin subtype tend to cluster together to the exclusion of other types, both in cell culture and during development. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, is single-pass type I membrane protein. It is expressed in endothelial tissues and brain andis involved in loss of heterozygosity events in breast and prostate cancer. CDH5 is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, CDH5 may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
VE-Cadherin / CD144 / CDH5抗体xy-1142xy STAT5(signal transducers and activators of transduction5)信号转导和转录激活因子5(STAT5)抗原
xy-1143xy STAT6(signal transducers and activators of transduction 6)信号转导和转录激活因子6抗原
xy-0629xy SULT1E1(Estrogen Sulfotranferase)雌激素硫酸转移酶抗原
xy-1499xy SUMO类泛素蛋白
xy-0885xy phospho-Tau protein (pThr489) peptide磷酸化微管相关蛋白多肽
xy-1369xy MAP-2(microtubule associated protein 2)微管相关蛋白2抗原
xy-1847xy MAP1A/Mtap1a(microtubule associated protein 1A)微管相关蛋白1A抗原
xy-1104xy TBX2/T-box2(T-box Protein 2)新型抑癌基因(多肽)
xy-1280xy TCF7L2(transcription factor 7-like 2)转录因子7类似物2抗原
xy-0822xy TDP-43/TARDBP (tar DNA binding protein)Tar DNA 结合蛋白43抗原
xy-1039xy Tenascin固生蛋白抗原
xy-2101xy TEM 1/CD248(Tumor endothelial marker 1 precursor)内涎蛋白/内皮唾液酸蛋白抗原
xy-0535xy TFF3 (trefoil factor3)三叶肽因子3(多肽)
xy-1144xy TFPI-2 (tissue factor pathway inhibitor-2)组织因子途径抑制剂-2抗原
xy-1838xy TIEG1/KLF10(TGF-beta inducible early response gene 1)TGF-β诱导早期应答基因1抗原
xy-0638xy TGF- BetaR1/ALK (TGF-beta receptor type I)转移生长因子–β受体1抗原
xy-1276xy Erdj5/DNAJC10Erdj5/DNAJC10多肽
xy-1334xy Tie1/JTK14 peptide上皮生长因子样域酪氨酸激酶1抗原
xy-1300xy Tie2(Porcine tyrosine kinase with immunoglobulin-like and EGF-like domains 2)上皮生长因子样域酪氨酸激酶2抗原
xy-1501xy Rarres2/TIG2/Chemerin(Retinoic acid receptor responder protein 2)视黄酸受体应答蛋白2抗原
xy-1444xy TLR3 (Toll-like receptor 3)Toll样受体3抗原
xy-1021xy TLR4/CD284 (Toll-like receptor 4)Toll样受体4抗原
xy-1197xy TLR5/CD285 (Toll-like receptor 5)Toll样受体5抗原
xy-0525xy TM(Thrombomodulin)血栓调节蛋白多肽
xy-1327xy Tn-C(Tenascin-C)C-Terminus腱糖蛋白-C(固生蛋白)C端抗原
xy-2081xy TNF-alpha肿瘤坏死因子-α抗原
xy-0093xy TNF- Beta(Tumor Necrosis Factor- Beta)肿瘤坏死因子-β抗原
xy-2104xy TNFAIP1(Tumor necrosis factor-alpha-induced protein 1)肿瘤坏死因子α诱导蛋白1抗原
xy-1203xy TOPO II Alpha/DNA TP II Alpha (DNA topoisomerase II Alpha)DNA拓普西异构酶Ⅱ抗原
xy-0329xy TRA16 (Testicular orphan nuclear receptor-4 (TR4)-associated protein)睾丸激素受体相关蛋白/孤儿素受体相关蛋白(抗原)
xy-1202xy TRADD(TNF receptor 1 associated via death domain)有死亡区的肿瘤坏死因子受体1相关蛋白抗原
xy-1212xy TRAF1肿瘤坏死因子受体相关因子1抗原
xy-1213xy TRAF2/TNF-R2 (TNF receptor-associated factor 2)肿瘤坏死因子受体相关因子2抗原