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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Recombinant Human Carbonic Anhydrase 2
- 供应商:
艾美捷科技有限公司
- 规格:
5µg&20µg&1mg
【产品形式】:艾美捷为您提供的【Carbonic Anhydrase 2 】重组人碳酸酐酶-2蛋白产品是过滤灭菌的无色溶液;其中人碳酸酐酶-2(Carbonic Anhydrase 2 )产品溶解于20mM Tris pH 8, 50mM NaCl, 10%甘油,1mM DTT溶液中。人碳酸酐酶-2(Carbonic Anhydrase 2 )溶液可以在4℃冷藏保存1周;如果想延长保存时间,建议分装(加载体蛋白如0.1% HSA或 BSA)后置于-18℃冻存。请避免反复冻融。
【背景资料】:The enzyme Carbonic anhydrase II having an accession number of NP_414668 is also called carbonate dehydratase which is part of the enzyme family that catalyses rapid inter-conversion of carbon dioxide & water to bicarbonate, carbonic acid and protons (CO2 + H2O ? HCO3? + H+), a reaction that occurs rather slowly in the absence of a catalyst. The majority of carbonic anhydrases enclose a zinc ion in their active site and therefore is classified as metalloenzymes. The most important function of Carbonic anhydrase is known to preserve acid-base balance in blood and other tissues, and to help transport carbon dioxide of tissues. Carbonic anhydrases have been found in all kingdoms of life. Carbonic anhydrase has 3 different classes: alpha, beta and gamma which share very little sequence or structural similarity, thus far they all perform the same function and require a zinc ion at the active site. Mammalian carbonic anhydrase is monomeric and belongs to the alpha class. Plant carbonic anhydrase is dimeric and belongs to the beta class. Methane-producing bacteria carbonic anhydrase is trimeric and grows in hot springs which forms the gamma class.
以色列ProSpec-Tany公司专注于细菌来源重组蛋白质生产。其独有细菌和哺乳动物表达和蛋白折叠技术使其成为国际一流科研级蛋白供应商。ProSpec-Tany是世界上能提供蛋白种类最多公司之一。领先生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。作为多家知名品牌代理,艾美捷与ProSpec一起为研究者们提供最好、最新细胞生物学研究工具而不断扩大产品及服务质量。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看中国生命科学试剂产品评论网站。
点击【Carbonic Anhydrase 2 】重组人碳酸酐酶-2查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-1454垂询Prospec中国区域授权总代理艾美捷科技有限公司。
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文献和实验碳酸酐酶 carbonic anhydrase carbonatehydrolyase
为催化 H2 CO3 CO2 + H2 O反应的酶,是锌蛋白质(动物原性), EC 4. 2. 1. 1,存在于脊椎动物的红血球和许多动物的各种组织以及植物的叶中。它在红血球中具有对碳酸和重碳酸离子的迅速转换的作用。在胃中对盐酸的分泌起作用,一般来说,具有调节体液 pH的作用。另外认为与植物的光合成有关系。
【Jounal club】NATURE MEDICINE: 利用蛋白组技术发现糖尿病眼底病变新机制
spectroscopy–based proteomics, we detected 117 proteins in human vitreous and elevated levels of extracellular carbonic anhydrase-I (CA-I) in vitreous from individuals with diabetic retinopathy, suggesting that retinal hemorrhage and erythrocyte lysis
The Application of the Chemical Array for Biological Study
library GLORIA (Gene Library of Osada Laboratory at RIKEN for chemical array analysis) has been established. Using the systematic platform, we detected novel inhibitors of carbonic anhydrase II. We also have shown that this screening method is useful
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