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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C储存
- 英文名:
Mutant Human Topoisomerase I
- 库存:
期货
- 供应商:
上海阿拉丁生化科技股份有限公司
- 规格:
M418761-1EA
英文名:Mutant Human Topoisomerase I
纯度或规格:0
SPU:M418761
CAS:-
存储温度:-20°C储存
运输条件:超低温运输
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文献和实验Purification of DNA Topoisomerase I from Human Placenta
DNA topoisomerase I (topo I) has been firmly established as the molecular target of the camptothecin group of anticancer drugs. These drugs include camptothecin, topotecan, 9-amino-camptothecin, and irinotecan
Assays for the Preferential Binding of Human Topoisomerase I to Supercoiled DNA
To assay the preferential binding of eukaryotic type IB topoisomerases to supercoiled DNA, two methods are described that make use of a catalytically inactive mutant form of the enzyme. In the gel shift assay, the preference for binding
Purification of Baculovirus-Expressed Human DNA Topoisomerase I
DNA topoisomerase I (topo I) can be isolated from cultured human cells in quantities that are more than sufficient for investigations into the ability of topo I to relax supercoiled DNA (250 μg/109 cells) (1 ,2 ). However, the production
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