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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C储存,避免反复冻融;超低温运输
- 英文名:
Human Topoisomerase I
- 库存:
期货
- 供应商:
上海阿拉丁生化科技股份有限公司
- 规格:
H418755-250U
基本描述
产品名称:Human Topoisomerase I
产品规格参数
储存条件:-20°C储存,避免反复冻融
运输条件:超低温运输
功能和特点
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文献和实验Purification of DNA Topoisomerase I from Human Placenta
DNA topoisomerase I (topo I) has been firmly established as the molecular target of the camptothecin group of anticancer drugs. These drugs include camptothecin, topotecan, 9-amino-camptothecin, and irinotecan
Purification of Baculovirus-Expressed Human DNA Topoisomerase I
DNA topoisomerase I (topo I) can be isolated from cultured human cells in quantities that are more than sufficient for investigations into the ability of topo I to relax supercoiled DNA (250 μg/109 cells) (1 ,2 ). However, the production
Assays for the Preferential Binding of Human Topoisomerase I to Supercoiled DNA
of nicked and supercoiled forms of the circular DNA to compete for the binding of a 3 H-labeled nicked DNA to the topoisomerase where the enzyme–DNA complexes are quantitated by the retention of the labeled DNA on a nitrocellulose membrane.
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