- ￥1600
- 齐源
- 108205
- 国产/进口
- 2025年07月10日
- FC
- 仓鼠
- 小鼠
6 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
Ly-49C/F/I/H
- 级别：
Ly-49C/F/I/H Antibody
- 目录编号：
Ly-49C/F/I/H Antibody
- 克隆性：
单克隆
- 抗原来源：
仓鼠
- 保质期：
Ly-49C/F/I/H Antibody
- 抗体英文名：
anti-mouse Ly-49C/F/I/H Antibody-FITC
- 抗体名：
Ly-49C/F/I/H Antibody
- 标记物：
FITC
- 宿主：
仓鼠
- 适应物种：
小鼠
- 免疫原：
Ly-49C/F/I/H Antibody
- 亚型：
Ly-49C/F/I/H Antibody
- 形态：
Ly-49C/F/I/H Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
0.5 mg/ml
- 规格：
50 µg
anti-mouse Ly-49C/F/I/H Antibody-FITC详细如下：
Description ：The 14B11 antibody reacts with a common epitope of Ly-49C/F/I/H family members also knownas Ly-49 inhibitory receptors C, F, and I and activating receptor H. It does not react with otherLy-49 members (i.e., Ly-49A, B, D, and G). Ly-49 is a type-II transmembrane, disulfide-linkedhomodimer with C-type lectin extracellular domains that binds to MHC class I. Ly-49C/F/I/H isexpressed on a subset of NK cells, NK-T cells and some CD8 cells. Ly-49C/F/I, like othermembers of this family, inhibits NK cell activation through the recognition and interaction ofcertain MHC class I haplotypes on potential target cells. Ly-49C, Ly-49F, and Ly-49I contain anITIM motif in their cytoplasmic tails, while Ly-49H lacks ITIM. Ly-49H is encoded by the Cmv1rgene, which promotes resistance to infection by mouse cytomegalovirus (CMV). BALB/c miceare reported to lack the Ly-49H and Ly-49I receptors. The 14B11 antibody, when bound to NKcells, is capable of inducing redirected cell lysis and blocking NK cell effector function.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Syrian Hamster
Immunogen ：IL-2-activated killer cells (LAK) from C57BL/6 mice
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography, and conjugated with FITC under optimalconditions.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Description ：The 14B11 antibody reacts with a common epitope of Ly-49C/F/I/H family members also knownas Ly-49 inhibitory receptors C, F, and I and activating receptor H. It does not react with otherLy-49 members (i.e., Ly-49A, B, D, and G). Ly-49 is a type-II transmembrane, disulfide-linkedhomodimer with C-type lectin extracellular domains that binds to MHC class I. Ly-49C/F/I/H isexpressed on a subset of NK cells, NK-T cells and some CD8 cells. Ly-49C/F/I, like othermembers of this family, inhibits NK cell activation through the recognition and interaction ofcertain MHC class I haplotypes on potential target cells. Ly-49C, Ly-49F, and Ly-49I contain anITIM motif in their cytoplasmic tails, while Ly-49H lacks ITIM. Ly-49H is encoded by the Cmv1rgene, which promotes resistance to infection by mouse cytomegalovirus (CMV). BALB/c miceare reported to lack the Ly-49H and Ly-49I receptors. The 14B11 antibody, when bound to NKcells, is capable of inducing redirected cell lysis and blocking NK cell effector function.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Syrian Hamster
Immunogen ：IL-2-activated killer cells (LAK) from C57BL/6 mice
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography, and conjugated with FITC under optimalconditions.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Corral L, et al. 1999. Hybridoma 18:359.
2. Hanke T, et al. 1999. Immunity 11:67.
Product Citations：
1. Cao D, et al. 2009. Transpl Immunol. 20:243. PubMed
1. Corral L, et al. 1999. Hybridoma 18:359.
2. Hanke T, et al. 1999. Immunity 11:67.
Product Citations：
1. Cao D, et al. 2009. Transpl Immunol. 20:243. PubMed
文献支持
抗小鼠 Ly-49C/F/I/H 流式标记FITC 抗体
￥1600
