相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD206 (MMR)
- 级别:
CD206 (MMR) Antibody
- 目录编号:
CD206 (MMR) Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD206 (MMR) Antibody
- 抗体英文名:
TotalSeq™-C0205 anti-human CD206 (MMR) Antibody
- 抗体名:
CD206 (MMR) Antibody
- 标记物:
CD206 (MMR) Antibody
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
CD206 (MMR) Antibody
- 亚型:
CD206 (MMR) Antibody
- 形态:
CD206 (MMR) Antibody
- 应用范围:
PG
- 保存条件:
2-8℃
- 浓度:
0.5 mg/ml
- 规格:
10 µg
Description :Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known asCD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) thatbelongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, andhepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range ofmicrobial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediatesendocytosis and phagocytosis, induces activation of macrophages and antigen presentation,plays an important role in host defense, and provides a link between innate and adaptiveimmunity.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Purified human mannose receptor
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 1 mM EDTA.
Preparation :The antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer underoptimal conditions.
Concentration :0.5 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application :PG - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis and the oligomer sequence is confirmed by sequencing. TotalSeq™-C antibodies arecompatible with 10x Genomics Chromium Single Cell Immune Profiling Solution.
To maximize performance, it is strongly recommended that the reagent be titrated for eachapplication, and that you centrifuge the antibody dilution before adding to the cells at 14,000xg at 2- 8°C for 10 minutes. Carefully pipette out the liquid avoiding the bottom of the tube and add to thecell suspension. For Proteogenomics analysis, the suggested starting amount of this reagent fortitration is ≤ 1.0 µg per million cells in 100 µL volume. Refer to the corresponding TotalSeq™protocol for specific staining instructions.
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验1. Noorman F, et al. 1997. J. Leukocyte Biol. 61:63. (WB, IHC, Block)
2. Barrett-Bergshoeff M, et al. 1997. Thromb Haemost. 77:718. (Block)
3. Kato M, et al. 2007. J. Immunol. 179:6052. (IF)
分别利用 CD3 与 CD28 的功能学抗体,以及 CD3/CD28 Streptamer® 激活扩增 T 细胞的实验步骤与实验结果。 CD3/CD28抗体法 1、实验步骤: 1.1 抗体包被 用无菌 PBS 将 anti-mouse CD3 抗体(克隆号:145-2C11)稀释至 5μg/ml,稀释后的抗体加入到 24 孔板中,每孔 400μl,4°C 包被过夜。(注:板子在加入抗体之前,先用无菌 PBS 润洗 2-3 遍,避免干孔); 1.2 小鼠脾脏淋巴细胞分离(次日) 1. 将 70μm
临床验证。抗人CD20(Rituximab)是第1个为FDA批准可用于临床癌症治疗的单抗。Rituximab与细胞表面的CD20分子结合后,可通过诱导ADCC和CDC清除高表达CD20分子的恶性B细胞,从而被认为在低分化的B细胞淋巴瘤和非霍奇金淋巴瘤的治疗中起重要作用。 近年来,另一个备受人们关注的治疗性单抗是抗Her-2的抗体。Her-2是表皮生长因子受体(EGFR)成员,参与乳腺癌的发生,且与乳腺癌患者的预后有关。相应单抗与Her-2结合可阻止Her-2与相应的生长因子的结合,抑制乳腺
CD20抗体Fab’片段,并在大肠杆菌中高效可溶性分泌表达[ 8 ] ,本研究的目的在于研究嵌合抗CD20Fab’片段的抗肿瘤活性及其作用机制。一、材料和方法1、材料MTT购自Sigma公司;Annexin-V为宝灵曼公司试剂盒;TRIZOL RNA提取试剂盒为美国Gibco公司产品;兔抗人bcl-2单克隆抗体和辣根过氧化物酶标记的羊抗兔IgG为北京中山生物技术有限公司产品,嵌合抗CD20Fab’片段为我室表达并纯化。β-actin引物(上游:5-TCATGTTTGAGACCTTCAA-3,下游










