• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        Adenoviral Gene Transfer into -Cell Lines

        互联网

        540
        The proper functioning of the insulin-producing β-cells in the pancreas depends on the action of various proteins whose function and level of expression are tightly regulated in order to maintain a well state. Alterations in these processes can lead to diseased states such as diabetes mellitus. In order to understand the complexity of these processes, it is imperative that scientists can alter the levels of expression of various genes in order to define their role in maintaining β-cell function. This can be accomplished through multiple techniques, of which the adenoviral gene transfer is the most efficient one. Gene-transfer techniques utilizing recombinant adenoviruses have become an important tool in controlling the expression level of genes of interest (1 ). Adenoviral gene transfer is also important in gene therapy of many inherited disorders (2 ). Recombinant adenoviruses are commonly used for the overexpression of transgenes and can also be used to downregulate genes of interest through the expression of antisense ribozymes and Cre-recombinase (1 ,2 ).
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序