- ￥4800
- Tanda
- 美国
- TD-26210
- 2025年10月30日
- ELISA, WB, IHC
- Mouse
- 脊椎动物
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide from the internal region of PIK3CA which includes the mutation of E542Q, human origin.
- 亚型：
lgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
单克隆
- 标记物：
FITC
- 适应物种：
脊椎动物
- 保质期：
24个月
- 抗原来源：
蛋白
- 目录编号：
TD-26210
- 级别：
科研级
- 库存：
999
- 供应商：
武汉天德
- 宿主：
Mouse
- 应用范围：
ELISA, WB, IHC
- 浓度：
1mg/ml
- 靶点：
E542Q
- 抗体英文名：
Anti PIK3CA(E542Q) Mouse Monoclonal Antibody
- 抗体名：
PIK3CA(E542Q)
- 规格：
100 μL
PIK3CA(E542Q)
| Cat. #: TD-26210 |
| Size: 100 µL |
| Gene Symbol: PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha |
| Description: Anti-PIK3CA(E542Q) Mouse Monoclonal Antibody |
| Background: Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Mutants of PIK3CA has been found in the pathogenesis of several cancers, including colon cancer, gliomas, gastric cancer, breast cancer, endometrial cancer, and lung cancer. |
| Immunogen: A synthetic peptide from the internal region of PIK3CA which includes the mutation of E542Q, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes E542Q mutant, but not wild type PIK3CA of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
|
Immunofluorescence:
|
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文献和实验q-values PAFAH1B3 10.211 8.1924e-009 1.8315e-005 1.8315e-005 RAB31 -13.702 2.8016e-008 3.1316e-005 3.1316e-005 LRP1 -9.0742 1.6453e-007 0.00012261 5.3953e-005 KIAA0367 -8.9398 1.7404e-007 9.7272e-005 5.3953e-005 ID2B
cancers (4 -6 ) have already contributed to the identification of the putative oncogene PIK3CA (7 ).
and frequency of mutations is very variable from ethnic population to population (4 ). The most common mutation, F508del (e.g., ΔF508 according to the old nomenclature), reaches frequencies of about 70% in Northern European populations. Besides F508del
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