- ￥4800
- Tanda
- 美国
- TD-26351-2
- 2025年10月24日
- ELISA, WB, IHC
- Mouse
- 脊椎动物
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Purified BRCA1(1720-1863) protein, human origin.
- 亚型：
lgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
单克隆
- 标记物：
FITC
- 适应物种：
脊椎动物
- 保质期：
24个月
- 抗原来源：
蛋白
- 目录编号：
TD-26351-2
- 级别：
科研级
- 库存：
999
- 供应商：
武汉天德
- 宿主：
Mouse
- 应用范围：
ELISA, WB, IHC
- 浓度：
1mg/ml
- 靶点：
1720-1863
- 抗体英文名：
Anti-BRCA1(1720-1863) Mouse Monoclonal Antibody
- 抗体名：
BRCA1 (1720-1863)
- 规格：
100 μL
BRCA1(1720-1863)
| Cat. #: TD-26351-2 |
| Gene Symbol: BRCA1, BRCC1, IRIS, PNCA4, PPP1R53, PSCP |
| Description: Anti-BRCA1(1720-1863) Mouse Monoclonal Antibody |
| Background: BRCA1 is normally expressed in cells of breast and other tissues, where it helps repair damaged DNA or destroy cells if DNA cannot be repaired. It is involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double-strand breaks. If BRCA1 itself is damaged by a BRCA1 mutation, damaged DNA is not repaired properly, and this increases the risk for breast cancer. |
| Immunogen: Purified BRCA1(1720-1863) protein, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes BRCA1(1720-1863) of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
Immunofluorescence:
Immunofluorescence of cells expressing BRCA1(1720-1863)protein with Anti-BRCA1(1720-1863) antibody. HEK293T cells was transfected with pCDNA3-GFP-BRCA1(1720-1863) plasmid, then fixed and stained with Anti-BRCA1(1720-1863) monoclonal antibody (Cat. #TD-26351-2). |
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文献和实验Development of a Scoring System to Screen for BRCA1/2 Mutations
Selection for genetic testing for pathogenic mutations in BRCA1 and BRCA2 is an important area of healthcare. While testing costs for mutational analysis are falling, costs of tests in North America remain in excess of $3,000. Most countries
Developing Functional Assays for BRCA1 Unclassified Variants
Women with a family history of breast cancer have mutations in one of the breast cancer susceptibility genes, BRCA1 or BRCA2 . Since the discovery of these two genes, around 100,000 women worldwide have undergone genetic testing
Ovarian Cancer Gene Therapy with BRCA1An Overview
The human breast and ovarian cancer susceptibility gene BRCA1 is a tumorsuppressor gene which is mutated and lost in hereditary breast and ovarian cancer, and has both alleles mutated in approximately 10-15% of cases of sporadic ovarian cancer
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