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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide from the internal region of FGFR1 which includes the mutation of P252T, human origin.
- 亚型:
lgG
- 形态:
液体
- 保存条件:
-20℃
- 克隆性:
单克隆
- 标记物:
FITC
- 适应物种:
脊椎动物
- 保质期:
24个月
- 抗原来源:
蛋白
- 目录编号:
TD-26253
- 级别:
科研级
- 库存:
999
- 供应商:
武汉天德
- 宿主:
Mouse
- 应用范围:
ELISA, WB, IHC
- 浓度:
1mg/ml
- 靶点:
P252T
- 抗体英文名:
Anti FGFR1(P252T) Mouse Monoclonal Antibody
- 抗体名:
FGFR1(P252T)
- 规格:
100 μL
FGFR1(P252T)
| Cat. #: TD-26253 |
| Gene Symbol: FGFR1, BFGFR, CD331, CEK, FGFBR, FLG |
| Description: Anti-FGFR1(P252T) Mouse Monoclonal Antibody |
| Background: The protein FGFR1 is highly conserved between members and throughout evolution. This particular family member of FGFR1 binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations of FGFR1 protein have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome. |
| Immunogen: A synthetic peptide from the internal region of FGFR1 which includes the mutation of P252T, human origin. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
| Concentration: 1 mg/ml |
| Host Species: Mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Preservative: No |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Recognizes P252T mutant, but not wild type FGFR1 of vertebrates. |
| Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
Western blot analysis of recombinant FGFR1(P252T) and wild type proteins. Purified His-tagged FGFR1(P252T) protein (22-376aa, ~45KDa, lane 2) and corresponding wild type protein (lane 1) were blotted with Anti-FGFR1(P252T) monoclonal antibody (Cat. #TD-26253). Immunofluorescence:
Immunofluorescence of cells expressing FGFR1 proteins with Anti-FGFR1(P252T) antibody. HEK293T cells were transfected with pCDNA3-GFP-FGFR1 (WT) plasmid (left column) or pCDNA3-GFP-FGFR1(P252T) plasmid (right column), then fixed and stained with Anti-FGFR1(P252T) monoclonal antibody (Cat. #TD-26253). |
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