18β-Glycyrrhetinic Acid

甘草甜素的主要代谢产物，甘草中的一种成分，具有抗溃疡、抗炎和免疫调节特性；100mg/kg/天剂量可降低糖尿病大鼠的脂质过氧化并增加抗氧化活性；抑制小鼠巨噬细胞中LPS诱导的TNF-α产生和NF-κB活化100-200μMA major metabolite of glycyrrhizin, a constituent of licorice that exhibits anti-ulcerative, anti-inflammatory, and immunomodulatory properties; at 100 mg/kg/day, reduces lipid peroxidation and increases antioxidant activity in diabetic rats; suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages 100-200 μM.