Chemical Name: (1,2,5,6-Tetrahydropyridin-4-yl)met
hylphosphinic acid
Biological Activity
A selective, competitive GABAC antagonist with only minimal effects on GABAA and GABAB receptors (Kb values are 2.1 μM (antagonist), 320 μM (antagonist) and EC50 ~ 500 μM (weak agonist) respectively). Displays 8-fold selectivity for human recombinant ρ1 receptors over ρ2 receptors.
Technical Data
M.Wt:
161.14
Formula:
C6H12NO2P
Solubility:
Soluble to 100 mM in water
Purity:
>98 %
Storage:
Store at RT
CAS No:
182485-36-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.