Cathelicidin Antimicrobial Pep

An Approach Combining Rapid cDNA Amplification and Chemical Synthesis for the Identification of Novel, Cathelicidin-Derived, Antimicrobial Peptides

Host defense in mammals involves a cooperative effort by a variety of antimicrobial peptides (1 ), which are produced by both phagocyte precursors and some epithelia. They are called on to combat invading pathogens at sites of infection

Computer-Based Analysis, Visualization, and Interpretation of Antimicrobial Peptide Activities

This chapter describes a computer-based method for analyzing the quantitative structure–activity relationships (QSAR) of antimicrobial peptides. Quantitative or qualitative activity measurements and known peptide sequences are used as input

Measuring Antimicrobial Peptide Activity on Epithelial Surfaces in Cell Culture

three-dimensional cultures of airway and gingival epithelium, which are grown at an air–liquid interface. Under these conditions, the cultures can be subjected to challenge with a variety of factors known to cause an increase in antimicrobial peptide gene expression